This article discusses cancer disparities by race/ethnicity and socioeconomic status, highlighting differences in cancer incidence, mortality, and survival. It uses data from the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) Program, the National Center for Health Statistics, and the National Health Interview Survey. The study found that residents of poorer counties have higher cancer death rates compared to more affluent counties. For example, men in poorer counties had 13% higher death rates from cancer than men in more affluent counties, while women had 3% higher rates. Differences in cancer survival also contribute to these disparities. Among both men and women, five-year survival for all cancers combined was 10 percentage points lower in poorer census tracts than in more affluent ones. Even when accounting for poverty rates, African American, American Indian/Alaskan Native, and Asian/Pacific Islander men and African American and American Indian/Alaskan Native women had lower five-year survival rates than non-Hispanic Whites. The study also found large variations in cancer survival by race and ethnicity for selected cancer sites. Opportunities to reduce cancer disparities exist in prevention, early detection, treatment, and palliative care. The article emphasizes the importance of addressing socioeconomic factors such as poverty, education, and health insurance in reducing cancer disparities. It also highlights the need for targeted interventions to improve access to cancer screening, treatment, and palliative care for disadvantaged populations. The study concludes that eliminating cancer disparities requires sustained efforts from governmental, private, and nonprofit organizations, as well as individuals engaged in cancer research, prevention, and care.This article discusses cancer disparities by race/ethnicity and socioeconomic status, highlighting differences in cancer incidence, mortality, and survival. It uses data from the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) Program, the National Center for Health Statistics, and the National Health Interview Survey. The study found that residents of poorer counties have higher cancer death rates compared to more affluent counties. For example, men in poorer counties had 13% higher death rates from cancer than men in more affluent counties, while women had 3% higher rates. Differences in cancer survival also contribute to these disparities. Among both men and women, five-year survival for all cancers combined was 10 percentage points lower in poorer census tracts than in more affluent ones. Even when accounting for poverty rates, African American, American Indian/Alaskan Native, and Asian/Pacific Islander men and African American and American Indian/Alaskan Native women had lower five-year survival rates than non-Hispanic Whites. The study also found large variations in cancer survival by race and ethnicity for selected cancer sites. Opportunities to reduce cancer disparities exist in prevention, early detection, treatment, and palliative care. The article emphasizes the importance of addressing socioeconomic factors such as poverty, education, and health insurance in reducing cancer disparities. It also highlights the need for targeted interventions to improve access to cancer screening, treatment, and palliative care for disadvantaged populations. The study concludes that eliminating cancer disparities requires sustained efforts from governmental, private, and nonprofit organizations, as well as individuals engaged in cancer research, prevention, and care.