This article presents cancer incidence, mortality, and survival statistics for 1995 in the United States, along with global comparisons. It provides estimates of new cancer cases and deaths by sex, site, and state, as well as cancer death rates in minority populations and international data. The estimates are based on data from the Surveillance, Epidemiology, and End Results (SEER) program and the US Census. The 1995 estimates use a quadratic function with an autoregressive model, which improved the fit for trends compared to previous linear models. The article also includes probabilities of developing cancer at certain ages and survival statistics by site, race, and stage at diagnosis. Cancer survival is reported as five-year relative survival rates, based on follow-up data through 1991. Mortality data are age-standardized to the 1970 US population. The article highlights that cancer incidence and mortality rates are higher among black Americans than whites. International mortality rates are age-adjusted to the WHO standard world population. Data limitations are noted, including the use of three-year-old data and the exclusion of certain cancer types. The estimates are offered as a rough guide and should be interpreted with caution. The article also includes data on cancer deaths in minority populations and global cancer death rates for 46 countries.This article presents cancer incidence, mortality, and survival statistics for 1995 in the United States, along with global comparisons. It provides estimates of new cancer cases and deaths by sex, site, and state, as well as cancer death rates in minority populations and international data. The estimates are based on data from the Surveillance, Epidemiology, and End Results (SEER) program and the US Census. The 1995 estimates use a quadratic function with an autoregressive model, which improved the fit for trends compared to previous linear models. The article also includes probabilities of developing cancer at certain ages and survival statistics by site, race, and stage at diagnosis. Cancer survival is reported as five-year relative survival rates, based on follow-up data through 1991. Mortality data are age-standardized to the 1970 US population. The article highlights that cancer incidence and mortality rates are higher among black Americans than whites. International mortality rates are age-adjusted to the WHO standard world population. Data limitations are noted, including the use of three-year-old data and the exclusion of certain cancer types. The estimates are offered as a rough guide and should be interpreted with caution. The article also includes data on cancer deaths in minority populations and global cancer death rates for 46 countries.