The American Cancer Society presents an overview of cancer statistics for 1998, including incidence, mortality, and survival rates. Due to the lack of a nationwide cancer registry and varying reporting quality among state registries, the estimates are based on population data from the US Census Bureau and cancer incidence rates from the National Cancer Institute’s SEER program. The methods involve a three-step procedure: multiplying age-specific incidence rates by population projections, fitting these estimates to an autoregressive quadratic model, and using the model to forecast 1998 cases. Adjustments were made for sites with changing incidence rates or large year-to-year variations. Estimates for new cancer cases in 1998 are about 1,228,600, excluding basal and squamous cell skin cancers and in situ carcinomas except bladder. Prostate cancer is the leading cancer in men, accounting for 29% of new cases, while breast cancer is the most common in women, contributing about 30% of new cases. In 1998, about 564,800 Americans are expected to die from cancer, with lung and bronchus, prostate, and colon and rectum cancers being the leading causes. Mortality rates for these cancers have been declining, reflecting the impact of early detection and treatment. The report also includes age-adjusted cancer death rates, survival rates, and other statistics. However, the estimates should be interpreted with caution due to their limitations, such as the time lag between data collection and estimation, and the potential for underrepresentation in smaller states. Despite these limitations, the estimates provide valuable insights into current cancer patterns in the United States.The American Cancer Society presents an overview of cancer statistics for 1998, including incidence, mortality, and survival rates. Due to the lack of a nationwide cancer registry and varying reporting quality among state registries, the estimates are based on population data from the US Census Bureau and cancer incidence rates from the National Cancer Institute’s SEER program. The methods involve a three-step procedure: multiplying age-specific incidence rates by population projections, fitting these estimates to an autoregressive quadratic model, and using the model to forecast 1998 cases. Adjustments were made for sites with changing incidence rates or large year-to-year variations. Estimates for new cancer cases in 1998 are about 1,228,600, excluding basal and squamous cell skin cancers and in situ carcinomas except bladder. Prostate cancer is the leading cancer in men, accounting for 29% of new cases, while breast cancer is the most common in women, contributing about 30% of new cases. In 1998, about 564,800 Americans are expected to die from cancer, with lung and bronchus, prostate, and colon and rectum cancers being the leading causes. Mortality rates for these cancers have been declining, reflecting the impact of early detection and treatment. The report also includes age-adjusted cancer death rates, survival rates, and other statistics. However, the estimates should be interpreted with caution due to their limitations, such as the time lag between data collection and estimation, and the potential for underrepresentation in smaller states. Despite these limitations, the estimates provide valuable insights into current cancer patterns in the United States.