The 2017 Cancer Statistics report estimates that 1,688,780 new cancer cases and 600,920 cancer deaths will occur in the United States. Cancer incidence rates are 20% higher in men than in women, while death rates are 40% higher. However, sex disparities vary by cancer type. For example, thyroid cancer incidence is 3 times higher in women than in men, despite similar death rates. Over the past decade, cancer incidence rates in men have declined by about 2% annually, while cancer death rates have declined by about 1.5% annually in both men and women. From 1991 to 2014, the overall cancer death rate dropped 25%, resulting in approximately 2.1 million fewer cancer deaths. Cancer death rates were 15% higher in blacks than in whites in 2014, but increasing access to care may help narrow the racial gap. The report also highlights disparities in cancer incidence and mortality by race and ethnicity, with higher rates among blacks and lower rates among Asian/Pacific Islanders. Regional variations in cancer rates are also noted, with lung cancer rates being significantly higher in some states. Cancer survival rates have improved over the past 30 years, with 5-year relative survival rates increasing by 20 percentage points for whites and 24 percentage points for blacks. However, survival rates for lung and pancreatic cancers remain low. The report also discusses cancer in children and adolescents, noting that cancer is the second most common cause of death among children aged 1 to 14 years. Despite progress in reducing cancer death rates, disparities persist, particularly for cancers associated with obesity. The report concludes that continued research and improved detection and treatment are needed to further reduce cancer mortality.The 2017 Cancer Statistics report estimates that 1,688,780 new cancer cases and 600,920 cancer deaths will occur in the United States. Cancer incidence rates are 20% higher in men than in women, while death rates are 40% higher. However, sex disparities vary by cancer type. For example, thyroid cancer incidence is 3 times higher in women than in men, despite similar death rates. Over the past decade, cancer incidence rates in men have declined by about 2% annually, while cancer death rates have declined by about 1.5% annually in both men and women. From 1991 to 2014, the overall cancer death rate dropped 25%, resulting in approximately 2.1 million fewer cancer deaths. Cancer death rates were 15% higher in blacks than in whites in 2014, but increasing access to care may help narrow the racial gap. The report also highlights disparities in cancer incidence and mortality by race and ethnicity, with higher rates among blacks and lower rates among Asian/Pacific Islanders. Regional variations in cancer rates are also noted, with lung cancer rates being significantly higher in some states. Cancer survival rates have improved over the past 30 years, with 5-year relative survival rates increasing by 20 percentage points for whites and 24 percentage points for blacks. However, survival rates for lung and pancreatic cancers remain low. The report also discusses cancer in children and adolescents, noting that cancer is the second most common cause of death among children aged 1 to 14 years. Despite progress in reducing cancer death rates, disparities persist, particularly for cancers associated with obesity. The report concludes that continued research and improved detection and treatment are needed to further reduce cancer mortality.