The article provides an overview of cancer statistics in the United States for 2018, including projected numbers of new cancer cases and deaths. It highlights trends in cancer incidence and mortality rates over the past decade, noting a stable incidence rate in women and a decline in men, while mortality rates have decreased annually for both genders. The combined cancer death rate has dropped by 26% from 1991 to 2015, resulting in approximately 2,378,600 fewer cancer deaths. The article also examines racial disparities in cancer mortality, with non-Hispanic blacks (NHBs) having a higher death rate than non-Hispanic whites (NHWs), particularly among individuals under 65 years old. State variations in cancer incidence and mortality rates are discussed, with some states showing significant racial disparities. The article concludes by emphasizing the need for broader application of cancer control strategies to reduce disparities and improve outcomes for all populations.The article provides an overview of cancer statistics in the United States for 2018, including projected numbers of new cancer cases and deaths. It highlights trends in cancer incidence and mortality rates over the past decade, noting a stable incidence rate in women and a decline in men, while mortality rates have decreased annually for both genders. The combined cancer death rate has dropped by 26% from 1991 to 2015, resulting in approximately 2,378,600 fewer cancer deaths. The article also examines racial disparities in cancer mortality, with non-Hispanic blacks (NHBs) having a higher death rate than non-Hispanic whites (NHWs), particularly among individuals under 65 years old. State variations in cancer incidence and mortality rates are discussed, with some states showing significant racial disparities. The article concludes by emphasizing the need for broader application of cancer control strategies to reduce disparities and improve outcomes for all populations.