The article provides a comprehensive overview of cancer prevalence, treatment, and survivorship in the United States as of January 1, 2012, and projects these numbers to January 1, 2022. It highlights the increasing number of cancer survivors due to population growth and improved survival rates. The American Cancer Society and the National Cancer Institute estimated that the number of cancer survivors would increase from 13.7 million in 2012 to nearly 18 million in 2022. The most common cancers among males are prostate, colorectal, and melanoma, while among females, they are breast, uterine corpus, and colorectal. The article discusses common cancer treatments, survival rates, and post-treatment concerns, emphasizing the need to understand the unique medical and psychosocial needs of survivors. It also introduces the National Cancer Survivorship Resource Center, which has developed tools for cancer survivors, caregivers, healthcare professionals, advocates, and policymakers. The article covers specific cancers such as breast, childhood cancers, colon and rectum, leukemias and lymphomas, lung and bronchus, melanoma, prostate, testis, thyroid, urinary bladder, and uterine corpus, detailing treatment options, survival rates, and common side effects.The article provides a comprehensive overview of cancer prevalence, treatment, and survivorship in the United States as of January 1, 2012, and projects these numbers to January 1, 2022. It highlights the increasing number of cancer survivors due to population growth and improved survival rates. The American Cancer Society and the National Cancer Institute estimated that the number of cancer survivors would increase from 13.7 million in 2012 to nearly 18 million in 2022. The most common cancers among males are prostate, colorectal, and melanoma, while among females, they are breast, uterine corpus, and colorectal. The article discusses common cancer treatments, survival rates, and post-treatment concerns, emphasizing the need to understand the unique medical and psychosocial needs of survivors. It also introduces the National Cancer Survivorship Resource Center, which has developed tools for cancer survivors, caregivers, healthcare professionals, advocates, and policymakers. The article covers specific cancers such as breast, childhood cancers, colon and rectum, leukemias and lymphomas, lung and bronchus, melanoma, prostate, testis, thyroid, urinary bladder, and uterine corpus, detailing treatment options, survival rates, and common side effects.