The study by Brown, Inskip, and Barracloough examines the excess mortality in a community cohort of 370 patients with schizophrenia over a 13-year period. The standardized mortality ratio (SMR) for all causes, natural causes, and unnatural causes was significantly higher than expected in the general population. The SMRs for circulatory, digestive, endocrine, nervous, and respiratory diseases, as well as for suicide and undetermined death, were also elevated. Smoking-related fatal diseases were more prominent in this cohort compared to the general population. The study suggests that some of the excess mortality could be reduced by improving medical care, addressing unhealthy lifestyles, and enhancing treatment compliance. The findings highlight the need for better management of medical conditions, mood disturbances, and psychosis in patients with schizophrenia.The study by Brown, Inskip, and Barracloough examines the excess mortality in a community cohort of 370 patients with schizophrenia over a 13-year period. The standardized mortality ratio (SMR) for all causes, natural causes, and unnatural causes was significantly higher than expected in the general population. The SMRs for circulatory, digestive, endocrine, nervous, and respiratory diseases, as well as for suicide and undetermined death, were also elevated. Smoking-related fatal diseases were more prominent in this cohort compared to the general population. The study suggests that some of the excess mortality could be reduced by improving medical care, addressing unhealthy lifestyles, and enhancing treatment compliance. The findings highlight the need for better management of medical conditions, mood disturbances, and psychosis in patients with schizophrenia.