Causes of the excess mortality of schizophrenia

Causes of the excess mortality of schizophrenia

2000 | STEVE BROWN, HAZEL INSKIP and BRIAN BARRACLOUGH
The study by Steve Brown, Hazel Inskip, and Brian Barracloth investigates the excess mortality in a community cohort of 370 patients with schizophrenia followed for 13 years. The standardized mortality ratio (SMR) showed significantly higher mortality rates for all causes, natural causes, and unnatural causes compared to the general population. Smoking-related diseases were more prevalent in this cohort. The excess mortality was attributed to factors such as poor medical care, failed recognition of medical conditions, poor treatment compliance, and unhealthy lifestyles, including smoking. Suicide was a major cause of unnatural deaths, with many patients under treatment at the time of death. The study highlights the importance of improving medical care, managing medical conditions, and addressing lifestyle factors to reduce mortality in schizophrenia patients. The findings suggest that most of the excess mortality can be explained by known mechanisms and should be susceptible to current interventions. The study also notes that the mortality rate was higher than previous studies, but the cohort was relatively small, and some SMRs had wide confidence intervals. The study concludes that reducing smoking, improving medical treatment, and addressing social and environmental risk factors are crucial in reducing the excess mortality in schizophrenia patients.The study by Steve Brown, Hazel Inskip, and Brian Barracloth investigates the excess mortality in a community cohort of 370 patients with schizophrenia followed for 13 years. The standardized mortality ratio (SMR) showed significantly higher mortality rates for all causes, natural causes, and unnatural causes compared to the general population. Smoking-related diseases were more prevalent in this cohort. The excess mortality was attributed to factors such as poor medical care, failed recognition of medical conditions, poor treatment compliance, and unhealthy lifestyles, including smoking. Suicide was a major cause of unnatural deaths, with many patients under treatment at the time of death. The study highlights the importance of improving medical care, managing medical conditions, and addressing lifestyle factors to reduce mortality in schizophrenia patients. The findings suggest that most of the excess mortality can be explained by known mechanisms and should be susceptible to current interventions. The study also notes that the mortality rate was higher than previous studies, but the cohort was relatively small, and some SMRs had wide confidence intervals. The study concludes that reducing smoking, improving medical treatment, and addressing social and environmental risk factors are crucial in reducing the excess mortality in schizophrenia patients.
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