Hippocampal astrocytes integrate past events in a centripetal manner, regulated by the locus coeruleus (LC). In adult mice, global astrocytic calcium signals reflect past neuronal and behavioral events on a timescale of seconds. Salient events, such as pupil dilations, facilitate calcium signal propagation from distal processes to the soma. This centripetal propagation is reproduced by optogenetic LC activation and reduced by pharmacological inhibition of α₁-adrenergic receptors. Astrocytes are computational units that slowly and conditionally integrate calcium signals during behaviorally relevant events. Astrocytes, traditionally viewed as supportive cells, are now recognized for their computational roles, such as representing sensory or internally generated information. Unlike neurons, astrocytic calcium signals are thought to be uncoordinated across compartments. However, this study shows that astrocytic activity can be temporally integrated, with calcium signals propagating from distal processes to the soma. This integration is gated by noradrenaline release from the LC, highlighting the role of neuromodulation in astrocytic signal processing. The study used two-photon calcium imaging in behaving mice to explore astrocytic activity in the hippocampal CA1 region. Global astrocytic activity was found to be temporally integrated, with calcium signals propagating centripetally from distal processes to the soma. This propagation was influenced by behavioral and neuronal factors, including pupil diameter, paw movement, and neuronal spike rate. The integration of past events was further supported by the observation that astrocytic activity was more strongly correlated with past events than with spatial landmarks. Centripetal propagation was found to be conditional on arousal and prior calcium levels. Optogenetic activation of the LC reproduced centripetal propagation, while blocking noradrenergic signaling reduced it. These findings suggest that astrocytic centripetal integration is a nonlinear process, dependent on the animal's state and facilitated by high levels of arousal. The study also showed that astrocytic activity is influenced by both global and local events. Global astrocytic activity was dominated by a global mode, while local events were observed in individual astrocytes. The results indicate that astrocytes can integrate past events in a centripetal manner, with the integration process being influenced by neuromodulatory signals and the animal's arousal state. This highlights the computational role of astrocytes in the brain, particularly in the context of behavior and arousal.Hippocampal astrocytes integrate past events in a centripetal manner, regulated by the locus coeruleus (LC). In adult mice, global astrocytic calcium signals reflect past neuronal and behavioral events on a timescale of seconds. Salient events, such as pupil dilations, facilitate calcium signal propagation from distal processes to the soma. This centripetal propagation is reproduced by optogenetic LC activation and reduced by pharmacological inhibition of α₁-adrenergic receptors. Astrocytes are computational units that slowly and conditionally integrate calcium signals during behaviorally relevant events. Astrocytes, traditionally viewed as supportive cells, are now recognized for their computational roles, such as representing sensory or internally generated information. Unlike neurons, astrocytic calcium signals are thought to be uncoordinated across compartments. However, this study shows that astrocytic activity can be temporally integrated, with calcium signals propagating from distal processes to the soma. This integration is gated by noradrenaline release from the LC, highlighting the role of neuromodulation in astrocytic signal processing. The study used two-photon calcium imaging in behaving mice to explore astrocytic activity in the hippocampal CA1 region. Global astrocytic activity was found to be temporally integrated, with calcium signals propagating centripetally from distal processes to the soma. This propagation was influenced by behavioral and neuronal factors, including pupil diameter, paw movement, and neuronal spike rate. The integration of past events was further supported by the observation that astrocytic activity was more strongly correlated with past events than with spatial landmarks. Centripetal propagation was found to be conditional on arousal and prior calcium levels. Optogenetic activation of the LC reproduced centripetal propagation, while blocking noradrenergic signaling reduced it. These findings suggest that astrocytic centripetal integration is a nonlinear process, dependent on the animal's state and facilitated by high levels of arousal. The study also showed that astrocytic activity is influenced by both global and local events. Global astrocytic activity was dominated by a global mode, while local events were observed in individual astrocytes. The results indicate that astrocytes can integrate past events in a centripetal manner, with the integration process being influenced by neuromodulatory signals and the animal's arousal state. This highlights the computational role of astrocytes in the brain, particularly in the context of behavior and arousal.