This review article explores the use of chitosan-based biomaterials in wound healing, highlighting their unique properties and potential applications. Chitosan, a biopolymer derived from chitin, is known for its biocompatibility, biodegradability, and wound-healing activity. The article discusses the various stages of wound healing, including hemostasis, inflammation, proliferation, and remodeling, and how chitosan can enhance each stage. Chitosan's ability to promote cell migration, reduce inflammation, and prevent infections makes it a promising material for wound dressings. The review also covers the antimicrobial, anti-inflammatory, and antioxidant activities of chitosan, which contribute to its effectiveness in wound healing. Additionally, the article examines the use of chitosan in medical implants, tissue engineering, drug delivery, and biosensors. Chitosan-based biomaterials, such as nanofibers, hydrogels, membranes, and sponges, are discussed in detail, along with their specific applications in diabetic wound healing, burns, and dental treatments. The article concludes by emphasizing the ongoing research and potential of chitosan-based biomaterials in advancing wound healing and related medical fields.This review article explores the use of chitosan-based biomaterials in wound healing, highlighting their unique properties and potential applications. Chitosan, a biopolymer derived from chitin, is known for its biocompatibility, biodegradability, and wound-healing activity. The article discusses the various stages of wound healing, including hemostasis, inflammation, proliferation, and remodeling, and how chitosan can enhance each stage. Chitosan's ability to promote cell migration, reduce inflammation, and prevent infections makes it a promising material for wound dressings. The review also covers the antimicrobial, anti-inflammatory, and antioxidant activities of chitosan, which contribute to its effectiveness in wound healing. Additionally, the article examines the use of chitosan in medical implants, tissue engineering, drug delivery, and biosensors. Chitosan-based biomaterials, such as nanofibers, hydrogels, membranes, and sponges, are discussed in detail, along with their specific applications in diabetic wound healing, burns, and dental treatments. The article concludes by emphasizing the ongoing research and potential of chitosan-based biomaterials in advancing wound healing and related medical fields.