Chitosan-based hemostatic dressings are natural polysaccharides derived from chitin, offering effective hemostasis and biocompatibility. This review discusses their structural characteristics, properties, and applications in surgical and non-surgical settings. Chitosan's cationic properties enable it to interact with negatively charged blood cells, promoting clot formation. Various chitosan-based dressings, such as HemCon, Celox, Axiostat, TraumaStat, and ChitoSeal, are highlighted for their hemostatic efficacy, biocompatibility, and ability to control bleeding in different wound types. These dressings are particularly useful in coagulopathic patients and in situations requiring rapid hemostasis. The review also emphasizes the advantages of chitosan-based dressings over conventional gauzes, including faster hemostasis, reduced bleeding time, and lower risk of complications. Surgical applications include wound management, vascular access site closure, and dental procedures. The study concludes that chitosan-based dressings are effective in reducing bleeding and improving patient outcomes, with ongoing research focusing on enhancing their properties through nanotechnology and composite materials.Chitosan-based hemostatic dressings are natural polysaccharides derived from chitin, offering effective hemostasis and biocompatibility. This review discusses their structural characteristics, properties, and applications in surgical and non-surgical settings. Chitosan's cationic properties enable it to interact with negatively charged blood cells, promoting clot formation. Various chitosan-based dressings, such as HemCon, Celox, Axiostat, TraumaStat, and ChitoSeal, are highlighted for their hemostatic efficacy, biocompatibility, and ability to control bleeding in different wound types. These dressings are particularly useful in coagulopathic patients and in situations requiring rapid hemostasis. The review also emphasizes the advantages of chitosan-based dressings over conventional gauzes, including faster hemostasis, reduced bleeding time, and lower risk of complications. Surgical applications include wound management, vascular access site closure, and dental procedures. The study concludes that chitosan-based dressings are effective in reducing bleeding and improving patient outcomes, with ongoing research focusing on enhancing their properties through nanotechnology and composite materials.