IntechOpen is a leading publisher of Open Access books, offering 7,200 open access books, with 191,000 international authors and editors, and over 210 million downloads. The book "Cholangiocarcinoma" by Samuel Romeo Obiekwe, Nathaly Suzett De La Roca, and Jean Saric discusses this malignant disease of the biliary ductal system, which is categorized into intrahepatic (5–10%), perihilar (60–70%), and distal (20–30%). The etiology remains unknown, but factors like chronic inflammation, infections, and genetic predispositions are implicated. Prognosis is poor unless detected early. Treatments include surgical resection, liver transplantation, and adjuvant therapies like chemotherapy and immunotherapy. The book also covers incidence, risk factors, clinical presentation, diagnosis, staging, and treatment options. Cholangiocarcinoma is rare in Western countries but more prevalent in regions like Thailand. Risk factors include bile duct cysts, parasitic infections, and chronic liver diseases. The book emphasizes the importance of early detection and multidisciplinary approaches for effective management.IntechOpen is a leading publisher of Open Access books, offering 7,200 open access books, with 191,000 international authors and editors, and over 210 million downloads. The book "Cholangiocarcinoma" by Samuel Romeo Obiekwe, Nathaly Suzett De La Roca, and Jean Saric discusses this malignant disease of the biliary ductal system, which is categorized into intrahepatic (5–10%), perihilar (60–70%), and distal (20–30%). The etiology remains unknown, but factors like chronic inflammation, infections, and genetic predispositions are implicated. Prognosis is poor unless detected early. Treatments include surgical resection, liver transplantation, and adjuvant therapies like chemotherapy and immunotherapy. The book also covers incidence, risk factors, clinical presentation, diagnosis, staging, and treatment options. Cholangiocarcinoma is rare in Western countries but more prevalent in regions like Thailand. Risk factors include bile duct cysts, parasitic infections, and chronic liver diseases. The book emphasizes the importance of early detection and multidisciplinary approaches for effective management.