Christensenella minuta, a new candidate next-generation probiotic: current evidence and future trajectories Christensenella minuta is a newly identified member of the human gut microbiome, belonging to the Christensenellaceae family. It has shown numerous beneficial properties and a wide range of uses. It is oxygen-tolerant, which is an advantage in the manufacturing and production of Christensenella minuta-based biotherapeutics. The review highlights the advantages of using Christensenella minuta as a probiotic and addresses challenges in its commercial production. The family Christensenellaceae has been associated with weight management and has been linked to metabolic disorders, inflammatory bowel disease, and other health conditions. Christensenella minuta has shown anti-inflammatory properties and the ability to protect the intestinal barrier. It has also been shown to improve metabolic indicators and reduce inflammation. The family Christensenellaceae is considered a key component of the gut microbiome and may play a crucial role in maintaining a healthy gut microbiome. The review also discusses the potential of Christensenella minuta as a probiotic and its possible mechanisms of action, including the production of short-chain fatty acids and bile salt hydrolase. The review concludes that Christensenella minuta has significant health benefits and could be used in the management and therapy of a wide range of health conditions. The review also discusses the challenges of commercial production and the potential of Christensenella minuta as a next-generation probiotic.Christensenella minuta, a new candidate next-generation probiotic: current evidence and future trajectories Christensenella minuta is a newly identified member of the human gut microbiome, belonging to the Christensenellaceae family. It has shown numerous beneficial properties and a wide range of uses. It is oxygen-tolerant, which is an advantage in the manufacturing and production of Christensenella minuta-based biotherapeutics. The review highlights the advantages of using Christensenella minuta as a probiotic and addresses challenges in its commercial production. The family Christensenellaceae has been associated with weight management and has been linked to metabolic disorders, inflammatory bowel disease, and other health conditions. Christensenella minuta has shown anti-inflammatory properties and the ability to protect the intestinal barrier. It has also been shown to improve metabolic indicators and reduce inflammation. The family Christensenellaceae is considered a key component of the gut microbiome and may play a crucial role in maintaining a healthy gut microbiome. The review also discusses the potential of Christensenella minuta as a probiotic and its possible mechanisms of action, including the production of short-chain fatty acids and bile salt hydrolase. The review concludes that Christensenella minuta has significant health benefits and could be used in the management and therapy of a wide range of health conditions. The review also discusses the challenges of commercial production and the potential of Christensenella minuta as a next-generation probiotic.