The chapter "Cleft Lip and Palate Epidemiology, Aetiology and Treatment" from the book *Fetal Diagnosis and Therapy* provides an overview of cleft lip and palate, a complex craniofacial disorder. The condition arises from disrupted facial development in the embryo and can lead to significant lifelong morbidity. Recent advancements in understanding the molecular mechanisms controlling lip and palate development, as well as improvements in surgical and medical care, have improved outcomes and quality of life for affected individuals. The book, edited by Martyn T. Cobourne, covers the epidemiology, genetic basis, developmental biology, and current management strategies for cleft lip and palate, making it a valuable resource for students, biologists, and clinicians interested in this subject.The chapter "Cleft Lip and Palate Epidemiology, Aetiology and Treatment" from the book *Fetal Diagnosis and Therapy* provides an overview of cleft lip and palate, a complex craniofacial disorder. The condition arises from disrupted facial development in the embryo and can lead to significant lifelong morbidity. Recent advancements in understanding the molecular mechanisms controlling lip and palate development, as well as improvements in surgical and medical care, have improved outcomes and quality of life for affected individuals. The book, edited by Martyn T. Cobourne, covers the epidemiology, genetic basis, developmental biology, and current management strategies for cleft lip and palate, making it a valuable resource for students, biologists, and clinicians interested in this subject.