The study examines the impact of inter-annual climate variability on crop yields for maize, rice, wheat, and soybean across 13,500 political units globally. It finds that climate variability accounts for 32-39% of the observed yield variability, with significant influence in many key agricultural regions. The analysis reveals distinct spatial patterns in the effects of temperature and precipitation variability on yields, highlighting areas where climate variability explains over 60% of yield variability. The study also discusses the implications for future food security and policy interventions to stabilize crop production and farmer incomes.The study examines the impact of inter-annual climate variability on crop yields for maize, rice, wheat, and soybean across 13,500 political units globally. It finds that climate variability accounts for 32-39% of the observed yield variability, with significant influence in many key agricultural regions. The analysis reveals distinct spatial patterns in the effects of temperature and precipitation variability on yields, highlighting areas where climate variability explains over 60% of yield variability. The study also discusses the implications for future food security and policy interventions to stabilize crop production and farmer incomes.