This study aimed to compare the periodontal health of pregnant women and puerperae after 6 months of home use of paraprobiotics. Paraprobiotics are inactivated microbial cells that provide health benefits to the host and are considered safe. Thirty pregnant women were enrolled and divided into two groups: the test group used a paraprobiotic-based toothpaste and mousse twice daily, while the control group used only the toothpaste. The study was conducted over 1, 3, and 6 months, with data collected during pregnancy and immediately after delivery. Indices such as clinical attachment loss (CAL), probing pocket depth (PPD), bleeding on probing (BOP), plaque control record (PCR), modified marginal gingival index (mMGI), papillary marginal gingival index (PMGI), and recession (R) were evaluated. The results showed that PCR decreased significantly in both groups, but BOP tended to decrease only in the test group. CAL, PPD, PMGI, and mMGI showed gradual decreases in both groups without significant differences. The combination of paraprobiotic-based toothpaste and mousse significantly reduced BOP and plaque control over time, although there were no significant differences with the use of the toothpaste alone. The combination also promoted a trend towards better stabilization of recessions. The study concluded that the combination of paraprobiotic-based products can improve periodontal health in pregnant women, particularly in reducing BOP and plaque control.This study aimed to compare the periodontal health of pregnant women and puerperae after 6 months of home use of paraprobiotics. Paraprobiotics are inactivated microbial cells that provide health benefits to the host and are considered safe. Thirty pregnant women were enrolled and divided into two groups: the test group used a paraprobiotic-based toothpaste and mousse twice daily, while the control group used only the toothpaste. The study was conducted over 1, 3, and 6 months, with data collected during pregnancy and immediately after delivery. Indices such as clinical attachment loss (CAL), probing pocket depth (PPD), bleeding on probing (BOP), plaque control record (PCR), modified marginal gingival index (mMGI), papillary marginal gingival index (PMGI), and recession (R) were evaluated. The results showed that PCR decreased significantly in both groups, but BOP tended to decrease only in the test group. CAL, PPD, PMGI, and mMGI showed gradual decreases in both groups without significant differences. The combination of paraprobiotic-based toothpaste and mousse significantly reduced BOP and plaque control over time, although there were no significant differences with the use of the toothpaste alone. The combination also promoted a trend towards better stabilization of recessions. The study concluded that the combination of paraprobiotic-based products can improve periodontal health in pregnant women, particularly in reducing BOP and plaque control.