February 14, 2024 | Abhishek Jaywant, PhD; Faith M. Gunning, PhD; Lauren E. Oberlin, PhD; Mauricio Santillana, PhD; Katherine Ognyanova, PhD; James N. Druckman, PhD; Matthew A. Baum, PhD; David Lazer, PhD; Roy H. Perlis, MD, MSc
A survey of 14,767 individuals with a history of SARS-CoV-2 infection found that 56.7% of those with post-COVID-19 condition reported experiencing at least one cognitive symptom daily, compared to 27.1% of those without post-COVID-19 condition. Cognitive symptoms were associated with greater depressive symptoms, more functional impairment, and lower likelihood of full-time employment. These symptoms were more common among younger individuals, women, and those with lower income. The study highlights the significant impact of cognitive symptoms on daily functioning and employment status, emphasizing the need for screening and addressing these symptoms in public health responses to post-COVID-19 condition. The findings suggest that cognitive symptoms are common in post-COVID-19 condition and often co-occur with depressive symptoms, contributing to functional impairment. The study underscores the importance of understanding the biological mechanisms underlying these symptoms to develop effective treatments. Limitations include the use of self-reported data and the non-probability sampling method, which may affect the generalizability of the results. The study provides valuable insights into the prevalence and impact of cognitive symptoms in post-COVID-19 condition, highlighting the need for further research and targeted interventions.A survey of 14,767 individuals with a history of SARS-CoV-2 infection found that 56.7% of those with post-COVID-19 condition reported experiencing at least one cognitive symptom daily, compared to 27.1% of those without post-COVID-19 condition. Cognitive symptoms were associated with greater depressive symptoms, more functional impairment, and lower likelihood of full-time employment. These symptoms were more common among younger individuals, women, and those with lower income. The study highlights the significant impact of cognitive symptoms on daily functioning and employment status, emphasizing the need for screening and addressing these symptoms in public health responses to post-COVID-19 condition. The findings suggest that cognitive symptoms are common in post-COVID-19 condition and often co-occur with depressive symptoms, contributing to functional impairment. The study underscores the importance of understanding the biological mechanisms underlying these symptoms to develop effective treatments. Limitations include the use of self-reported data and the non-probability sampling method, which may affect the generalizability of the results. The study provides valuable insights into the prevalence and impact of cognitive symptoms in post-COVID-19 condition, highlighting the need for further research and targeted interventions.