Cognitive Symptoms of Post-COVID-19 Condition and Daily Functioning

Cognitive Symptoms of Post-COVID-19 Condition and Daily Functioning

February 14, 2024 | Abhishek Jaywant, PhD; Faith M. Gunning, PhD; Lauren E. Oberlin, PhD; Mauricio Santillana, PhD; Katherine Ognyanova, PhD; James N. Druckman, PhD; Matthew A. Baum, PhD; David Lazer, PhD; Roy H. Perlis, MD, MSc
This study investigates the prevalence and correlates of self-reported cognitive symptoms in individuals with post-COVID-19 condition, compared to those who did not develop this condition. The survey, conducted between December 22, 2022, and May 5, 2023, included 14,767 participants aged 18 years and older. Key findings include: - **Prevalence of Cognitive Symptoms**: Among those with post-COVID-19 condition, 56.7% reported experiencing at least one cognitive symptom daily, compared to 27% in those without post-COVID-19 condition. - **Demographic and Functional Outcomes**: Cognitive symptoms were more common among younger individuals, women, and those with lower incomes. They were also associated with greater functional impairment, lesser likelihood of full-time employment, and more severe depressive symptoms. - **Association with Depressive Symptoms**: Cognitive symptoms were significantly associated with greater severity of depressive symptoms, both unadjusted and adjusted for sociodemographic factors. - **Functional Impairment**: Individuals with more cognitive symptoms reported greater interference with daily functioning and were less likely to be employed full-time. The study suggests that cognitive symptoms are common in post-COVID-19 condition and are associated with significant functional and quality of life impacts, highlighting the need for better understanding and management of these symptoms.This study investigates the prevalence and correlates of self-reported cognitive symptoms in individuals with post-COVID-19 condition, compared to those who did not develop this condition. The survey, conducted between December 22, 2022, and May 5, 2023, included 14,767 participants aged 18 years and older. Key findings include: - **Prevalence of Cognitive Symptoms**: Among those with post-COVID-19 condition, 56.7% reported experiencing at least one cognitive symptom daily, compared to 27% in those without post-COVID-19 condition. - **Demographic and Functional Outcomes**: Cognitive symptoms were more common among younger individuals, women, and those with lower incomes. They were also associated with greater functional impairment, lesser likelihood of full-time employment, and more severe depressive symptoms. - **Association with Depressive Symptoms**: Cognitive symptoms were significantly associated with greater severity of depressive symptoms, both unadjusted and adjusted for sociodemographic factors. - **Functional Impairment**: Individuals with more cognitive symptoms reported greater interference with daily functioning and were less likely to be employed full-time. The study suggests that cognitive symptoms are common in post-COVID-19 condition and are associated with significant functional and quality of life impacts, highlighting the need for better understanding and management of these symptoms.
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