The paper presents a method for creating complex two-dimensional shapes and tubes using single-stranded DNA tiles (SSTs). SSTs are 42-base strands of DNA with concatenated sticky ends that bind to four neighbors during self-assembly. The authors designed a self-assembled rectangle as a molecular canvas, where each SST strand acts as a pixel. By selecting the appropriate subset of SST strands, complex shapes can be constructed. The method was successfully applied to create 107 distinct and complex two-dimensional shapes, demonstrating its simplicity, modularity, and robustness. The SST approach is compared to DNA origami, highlighting the complementary nature of both methods in creating complex structures through cooperative self-assembly. The study also explores the design and assembly of tubes and the use of a computer program to automate the process of designing and assembling complex shapes.The paper presents a method for creating complex two-dimensional shapes and tubes using single-stranded DNA tiles (SSTs). SSTs are 42-base strands of DNA with concatenated sticky ends that bind to four neighbors during self-assembly. The authors designed a self-assembled rectangle as a molecular canvas, where each SST strand acts as a pixel. By selecting the appropriate subset of SST strands, complex shapes can be constructed. The method was successfully applied to create 107 distinct and complex two-dimensional shapes, demonstrating its simplicity, modularity, and robustness. The SST approach is compared to DNA origami, highlighting the complementary nature of both methods in creating complex structures through cooperative self-assembly. The study also explores the design and assembly of tubes and the use of a computer program to automate the process of designing and assembling complex shapes.