Conductive polymers: Towards a smart biomaterial for tissue engineering

Conductive polymers: Towards a smart biomaterial for tissue engineering

2014 | Richard Balint, Nigel J. Cassidy, Sarah H. Cartmell
Conductive polymers are promising materials for tissue engineering due to their ability to be tailored for specific applications. This review focuses on polypyrrole (PPy), polyaniline (PANI), and poly(3,4-ethylenedioxythiophene) (PEDOT). These polymers can be synthesized, modified, or combined with other materials to create biocompatible, biodegradable, and electrically conductive materials. They can be functionalized to bind biological molecules, enabling applications in biosensors, neural implants, drug delivery, and tissue engineering scaffolds. Conductive polymers can be stimulated by electrical signals to release drugs, influence cell behavior, and adjust their properties. PPy is highly biocompatible and has good electrical conductivity, but is difficult to process. PANI is easy to synthesize and has good environmental stability, but is less biocompatible. PEDOT has excellent electrical and chemical stability, and is used in biosensing and neural electrodes. Doping is essential for conductivity, and can be controlled to adjust the polymer's properties. Conductive polymers can be combined with other materials to create composites, hydrogels, or electrospun fibers, which can be used in biomedical applications. The biocompatibility of these polymers varies, and their degradation can be controlled by modifying their structure. Conductive polymers have shown promise in drug delivery, as they can be used to release drugs in response to electrical signals. However, their use in biological applications is limited by factors such as their biocompatibility, degradation, and the ability to bind and release drugs. Overall, conductive polymers are a promising area of research for tissue engineering and biomedical applications.Conductive polymers are promising materials for tissue engineering due to their ability to be tailored for specific applications. This review focuses on polypyrrole (PPy), polyaniline (PANI), and poly(3,4-ethylenedioxythiophene) (PEDOT). These polymers can be synthesized, modified, or combined with other materials to create biocompatible, biodegradable, and electrically conductive materials. They can be functionalized to bind biological molecules, enabling applications in biosensors, neural implants, drug delivery, and tissue engineering scaffolds. Conductive polymers can be stimulated by electrical signals to release drugs, influence cell behavior, and adjust their properties. PPy is highly biocompatible and has good electrical conductivity, but is difficult to process. PANI is easy to synthesize and has good environmental stability, but is less biocompatible. PEDOT has excellent electrical and chemical stability, and is used in biosensing and neural electrodes. Doping is essential for conductivity, and can be controlled to adjust the polymer's properties. Conductive polymers can be combined with other materials to create composites, hydrogels, or electrospun fibers, which can be used in biomedical applications. The biocompatibility of these polymers varies, and their degradation can be controlled by modifying their structure. Conductive polymers have shown promise in drug delivery, as they can be used to release drugs in response to electrical signals. However, their use in biological applications is limited by factors such as their biocompatibility, degradation, and the ability to bind and release drugs. Overall, conductive polymers are a promising area of research for tissue engineering and biomedical applications.
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[slides] Conductive polymers%3A towards a smart biomaterial for tissue engineering. | StudySpace