Connective tissue inspired elastomer-based hydrogel for artificial skin via radiation-induced penetrating polymerization

Connective tissue inspired elastomer-based hydrogel for artificial skin via radiation-induced penetrating polymerization

20 January 2024 | Yuan Tian, Zhihao Wang, Shuiyan Cao, Dong Liu, Yukun Zhang, Chong Chen, Zhiwen Jiang, Jun Ma & Yunlong Wang
A novel elastomer-based hydrogel inspired by connective tissue has been developed for artificial skin applications. This hydrogel is created through a radiation-induced penetrating polymerization method, converting traditional elastomers into tough hydrogels. The hydrogel combines the elastic properties of elastomers with the hydrophilic characteristics of hydrogels, resulting in a material that closely mimics the mechanical and surface properties of human skin. It exhibits a Young's modulus and friction coefficient similar to human skin, along with superior compression and puncture resistance compared to other hydrogels. The hydrogel also demonstrates shape adaptability and responsive behavior, making it suitable for various bionic applications, including artificial skin, fluid flow control, and wound dressings. The hydrogel is synthesized by grafting polyacrylic acid (PAA) onto silicone rubber using gamma-ray irradiation. This process allows for the uniform distribution of grafted chains across the elastomer, resulting in a hydrogel with excellent mechanical properties, ion sensitivity, and adhesion to human skin. The hydrogel can be tailored by adjusting the grafting conditions, enabling the creation of materials with varying degrees of hydrophilicity and mechanical strength. The hydrogel's properties make it suitable for applications such as wound dressings, controllable flow conduits, shape memory-based fracture connections, and manipulator cladding materials. The hydrogel's unique properties, including its ability to respond to external stimuli and adapt its shape, make it a promising candidate for various bionic applications. It has been demonstrated to have excellent mechanical performance, with a high compressive strength and puncture resistance, and it can be used in surgical fixation and wound healing applications. The hydrogel's biocompatibility and ability to respond to ions make it suitable for medical applications, such as surgical repair and internal fixation. The hydrogel has also been shown to promote wound healing in mice, with similar effects to traditional wound dressings. Overall, this hydrogel represents a significant advancement in the development of materials that can mimic the properties of human skin and other biological tissues.A novel elastomer-based hydrogel inspired by connective tissue has been developed for artificial skin applications. This hydrogel is created through a radiation-induced penetrating polymerization method, converting traditional elastomers into tough hydrogels. The hydrogel combines the elastic properties of elastomers with the hydrophilic characteristics of hydrogels, resulting in a material that closely mimics the mechanical and surface properties of human skin. It exhibits a Young's modulus and friction coefficient similar to human skin, along with superior compression and puncture resistance compared to other hydrogels. The hydrogel also demonstrates shape adaptability and responsive behavior, making it suitable for various bionic applications, including artificial skin, fluid flow control, and wound dressings. The hydrogel is synthesized by grafting polyacrylic acid (PAA) onto silicone rubber using gamma-ray irradiation. This process allows for the uniform distribution of grafted chains across the elastomer, resulting in a hydrogel with excellent mechanical properties, ion sensitivity, and adhesion to human skin. The hydrogel can be tailored by adjusting the grafting conditions, enabling the creation of materials with varying degrees of hydrophilicity and mechanical strength. The hydrogel's properties make it suitable for applications such as wound dressings, controllable flow conduits, shape memory-based fracture connections, and manipulator cladding materials. The hydrogel's unique properties, including its ability to respond to external stimuli and adapt its shape, make it a promising candidate for various bionic applications. It has been demonstrated to have excellent mechanical performance, with a high compressive strength and puncture resistance, and it can be used in surgical fixation and wound healing applications. The hydrogel's biocompatibility and ability to respond to ions make it suitable for medical applications, such as surgical repair and internal fixation. The hydrogel has also been shown to promote wound healing in mice, with similar effects to traditional wound dressings. Overall, this hydrogel represents a significant advancement in the development of materials that can mimic the properties of human skin and other biological tissues.
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