The Consensus on the Treatment of Second-Degree Burn Wounds (2024 edition) was developed based on evidence-based medicine and expert opinion to provide standardized clinical treatment plans for second-degree burn wounds. This consensus includes 58 recommendations covering prehospital first aid, nonsurgical treatment, surgical treatment, and infection treatment. It aims to standardize the terminology and treatment of second-degree burn wounds, including the first-time division of deep second-degree burn wounds into shallow deep and profound deep categories. The consensus also establishes grading and diagnostic criteria for burn wound infection, classifying the severity of wound infection as mild, moderate, or severe. It provides a treatment protocol for second-degree burn wounds with strong operability and practicability for standardizing diagnosis, classification, and treatment. The consensus was developed through a multi-step process involving clinical questioning, expert discussions, and reviews. It includes systematic literature reviews and evidence grading using the GRADE system. The recommendations were formulated based on the consensus of experts, with the strength of recommendations determined by the degree of consistency among experts. The consensus provides specific recommendations for prehospital first aid, including immediate removal from the heat source, cooling the wound as soon as possible, and preserving blister skin. For chemical burns, it recommends immediate removal of contaminated clothing, rinsing with running water, and avoiding neutralizing agents. For electrical burns, it emphasizes ensuring rescuer safety, disconnecting the power source, and promptly transporting the victim to a hospital. For nonsurgical treatment, the consensus recommends using clinical evaluation and non-contact diagnostic techniques for depth diagnosis, classifying second-degree burn wounds into superficial, shallow deep, profound deep, and uncertain-depth categories, and using the nine-point scale, palm method, and Lund–Browder chart for wound area assessment. The consensus also provides guidance on wound management, including the use of sterile dressings and avoiding improper wound handling. The consensus aims to provide a comprehensive and standardized approach to the treatment of second-degree burn wounds, improving clinical outcomes and consistency in treatment.The Consensus on the Treatment of Second-Degree Burn Wounds (2024 edition) was developed based on evidence-based medicine and expert opinion to provide standardized clinical treatment plans for second-degree burn wounds. This consensus includes 58 recommendations covering prehospital first aid, nonsurgical treatment, surgical treatment, and infection treatment. It aims to standardize the terminology and treatment of second-degree burn wounds, including the first-time division of deep second-degree burn wounds into shallow deep and profound deep categories. The consensus also establishes grading and diagnostic criteria for burn wound infection, classifying the severity of wound infection as mild, moderate, or severe. It provides a treatment protocol for second-degree burn wounds with strong operability and practicability for standardizing diagnosis, classification, and treatment. The consensus was developed through a multi-step process involving clinical questioning, expert discussions, and reviews. It includes systematic literature reviews and evidence grading using the GRADE system. The recommendations were formulated based on the consensus of experts, with the strength of recommendations determined by the degree of consistency among experts. The consensus provides specific recommendations for prehospital first aid, including immediate removal from the heat source, cooling the wound as soon as possible, and preserving blister skin. For chemical burns, it recommends immediate removal of contaminated clothing, rinsing with running water, and avoiding neutralizing agents. For electrical burns, it emphasizes ensuring rescuer safety, disconnecting the power source, and promptly transporting the victim to a hospital. For nonsurgical treatment, the consensus recommends using clinical evaluation and non-contact diagnostic techniques for depth diagnosis, classifying second-degree burn wounds into superficial, shallow deep, profound deep, and uncertain-depth categories, and using the nine-point scale, palm method, and Lund–Browder chart for wound area assessment. The consensus also provides guidance on wound management, including the use of sterile dressings and avoiding improper wound handling. The consensus aims to provide a comprehensive and standardized approach to the treatment of second-degree burn wounds, improving clinical outcomes and consistency in treatment.