This study reports the direct observation and controlled creation of one-dimensional (1D) and two-dimensional (2D) periodic ripples in suspended graphene sheets using spontaneously and thermally induced longitudinal strains on patterned substrates. The ripples can be oriented and controlled by manipulating boundary conditions and the difference in thermal expansion coefficients (TEC) between graphene and the substrate. The TEC of graphene is anomalously large and negative, approximately -7×10⁻⁶ K⁻¹ at 300K, which is about 5-6 times larger than that of bulk graphite in the basal plane. This thermo-mechanical manipulation enables novel strain-based engineering of graphene devices. The ripples are formed due to the interplay between the thermal expansion of the substrate and the membrane. The study shows that the ripples can be controlled by thermal manipulation, with the amplitude and wavelength of the ripples related to the maximum temperature rise during annealing. The orientation of the ripples is determined by the substrate-imposed boundary conditions. The study also provides the first experimental measurement of graphene's TEC, which is significantly larger and negative than that of graphite. The ripples' effects on graphene's electrical properties are investigated, showing that small ripples do not introduce significant scattering, consistent with prior results. The study also demonstrates that suspended graphene devices have higher mobility and sharper Dirac points compared to substrate-supported devices, indicating smaller density of charged impurities. The results suggest that the elimination of the substrate enhances device mobility, which is consistent with prior findings from high-mobility suspended graphene devices. The ability to controllably create ripples in graphene opens the door for systematic investigation of ripples' effects on graphene's electrical properties and strain-based engineering of graphene devices. The study also has implications for understanding results reported in previous studies, where suspended graphene devices display unusual G(T) behaviors with large sample-to-sample variations. The findings highlight the unique thermal properties of graphene and its potential for novel device applications.This study reports the direct observation and controlled creation of one-dimensional (1D) and two-dimensional (2D) periodic ripples in suspended graphene sheets using spontaneously and thermally induced longitudinal strains on patterned substrates. The ripples can be oriented and controlled by manipulating boundary conditions and the difference in thermal expansion coefficients (TEC) between graphene and the substrate. The TEC of graphene is anomalously large and negative, approximately -7×10⁻⁶ K⁻¹ at 300K, which is about 5-6 times larger than that of bulk graphite in the basal plane. This thermo-mechanical manipulation enables novel strain-based engineering of graphene devices. The ripples are formed due to the interplay between the thermal expansion of the substrate and the membrane. The study shows that the ripples can be controlled by thermal manipulation, with the amplitude and wavelength of the ripples related to the maximum temperature rise during annealing. The orientation of the ripples is determined by the substrate-imposed boundary conditions. The study also provides the first experimental measurement of graphene's TEC, which is significantly larger and negative than that of graphite. The ripples' effects on graphene's electrical properties are investigated, showing that small ripples do not introduce significant scattering, consistent with prior results. The study also demonstrates that suspended graphene devices have higher mobility and sharper Dirac points compared to substrate-supported devices, indicating smaller density of charged impurities. The results suggest that the elimination of the substrate enhances device mobility, which is consistent with prior findings from high-mobility suspended graphene devices. The ability to controllably create ripples in graphene opens the door for systematic investigation of ripples' effects on graphene's electrical properties and strain-based engineering of graphene devices. The study also has implications for understanding results reported in previous studies, where suspended graphene devices display unusual G(T) behaviors with large sample-to-sample variations. The findings highlight the unique thermal properties of graphene and its potential for novel device applications.