The review discusses the current progress in lignocellulosic bioethanol production, focusing on technological and economic aspects. It highlights advancements in pretreatment, hydrolysis, and fermentation stages, which are crucial for improving the efficiency and cost-effectiveness of bioethanol production. Innovations such as deep eutectic solvents and mechanocatalysis offer significant advantages over traditional methods, enhancing solid loading and reducing costs. Improved pretreatment methods, enzyme exploration, and genetic engineering contribute to the economic viability of bioethanol production. Techno-economic analysis is used to evaluate cost-effective strategies, aiming to enhance the competitiveness of lignocellulosic bioethanol. The review also addresses the challenges in bioethanol production, including the need for efficient pretreatment, hydrolysis, and fermentation processes. Current strategies focus on reducing costs, improving enzyme efficiency, and developing integrated biorefineries. The use of deep eutectic solvents and mechanocatalysis is highlighted as promising approaches to overcome existing limitations. The review emphasizes the importance of reducing inhibitor formation, improving saccharification efficiency, and optimizing fermentation processes to achieve higher ethanol yields and lower production costs. The integration of these strategies is expected to promote the industrial production of lignocellulosic bioethanol, contributing to sustainable energy solutions.The review discusses the current progress in lignocellulosic bioethanol production, focusing on technological and economic aspects. It highlights advancements in pretreatment, hydrolysis, and fermentation stages, which are crucial for improving the efficiency and cost-effectiveness of bioethanol production. Innovations such as deep eutectic solvents and mechanocatalysis offer significant advantages over traditional methods, enhancing solid loading and reducing costs. Improved pretreatment methods, enzyme exploration, and genetic engineering contribute to the economic viability of bioethanol production. Techno-economic analysis is used to evaluate cost-effective strategies, aiming to enhance the competitiveness of lignocellulosic bioethanol. The review also addresses the challenges in bioethanol production, including the need for efficient pretreatment, hydrolysis, and fermentation processes. Current strategies focus on reducing costs, improving enzyme efficiency, and developing integrated biorefineries. The use of deep eutectic solvents and mechanocatalysis is highlighted as promising approaches to overcome existing limitations. The review emphasizes the importance of reducing inhibitor formation, improving saccharification efficiency, and optimizing fermentation processes to achieve higher ethanol yields and lower production costs. The integration of these strategies is expected to promote the industrial production of lignocellulosic bioethanol, contributing to sustainable energy solutions.