The article provides a brief review of the changes in the Diagnostic and Statistical Manual of Mental Disorders (DSM) from DSM-IV-TR to DSM-5. The publication of the fifth edition of the DSM in May 2013 is marked as one of the most anticipated events in the mental health field. Key changes include recommendations for further study of attenuated psychosis syndrome and mixed anxiety depressive disorder due to concerns about their reliability. A footnote was added to the major depressive disorder criteria to clarify the difference between normal bereavement and a mental disorder. The diagnostic criteria for pedophilic disorder in personality disorders were modified. Communication disorders now include two diagnoses: Language disorders and speech disorders. Simple somatic symptom disorder and complex somatic symptom disorder were combined into a single disorder, somatic symptom disorder. Non-suicidal self-injury disorder and persistent complex bereavement disorder were also introduced. The article highlights significant changes in diagnostic criteria, classifications, subscales, and proposed new terms in the DSM-5.The article provides a brief review of the changes in the Diagnostic and Statistical Manual of Mental Disorders (DSM) from DSM-IV-TR to DSM-5. The publication of the fifth edition of the DSM in May 2013 is marked as one of the most anticipated events in the mental health field. Key changes include recommendations for further study of attenuated psychosis syndrome and mixed anxiety depressive disorder due to concerns about their reliability. A footnote was added to the major depressive disorder criteria to clarify the difference between normal bereavement and a mental disorder. The diagnostic criteria for pedophilic disorder in personality disorders were modified. Communication disorders now include two diagnoses: Language disorders and speech disorders. Simple somatic symptom disorder and complex somatic symptom disorder were combined into a single disorder, somatic symptom disorder. Non-suicidal self-injury disorder and persistent complex bereavement disorder were also introduced. The article highlights significant changes in diagnostic criteria, classifications, subscales, and proposed new terms in the DSM-5.