The Dali server, a network service for comparing protein structures in 3D, has been updated to enhance its analytics for sequence and structure conservation. The server performs three types of structure comparisons: Protein Data Bank (PDB) search, pairwise comparison, and all against all structure comparison. The latest updates include the replacement of Jmol with PV for protein visualization, the addition of an all-against-all comparison option, and the introduction of stacked sequence logos to visualize conserved sequence motifs. These enhancements improve the user interface and provide more detailed insights into structural relationships and sequence similarities. The server's capabilities are demonstrated through an example analysis of the amidohydrolase and PHP superfamilies, highlighting its utility in understanding protein functions and identifying misannotations.The Dali server, a network service for comparing protein structures in 3D, has been updated to enhance its analytics for sequence and structure conservation. The server performs three types of structure comparisons: Protein Data Bank (PDB) search, pairwise comparison, and all against all structure comparison. The latest updates include the replacement of Jmol with PV for protein visualization, the addition of an all-against-all comparison option, and the introduction of stacked sequence logos to visualize conserved sequence motifs. These enhancements improve the user interface and provide more detailed insights into structural relationships and sequence similarities. The server's capabilities are demonstrated through an example analysis of the amidohydrolase and PHP superfamilies, highlighting its utility in understanding protein functions and identifying misannotations.