Julius Wolff's "Das Gesetz der Transformation der Knochen" is a comprehensive work that summarizes a series of studies dating back to 1869. It is based on the mathematical insights of H. v. Meyer and the work of Culmann, who discovered the mathematical significance of bone architecture. Wolff introduced a new method using bone sections to study bone structure, leading to important discoveries such as the right-angle crossing of spongiosa trabeculae and the neutral axis of the femoral head. He proposed the "Transformation Law of Bones," which states that bone architecture changes in response to mechanical stress, and that these changes are governed by mathematical principles. Wolff also emphasized the importance of bone function in determining its shape, arguing that bone structure is determined by the mechanical load it bears. He introduced the concept of "Transformation Force," a therapeutic force that can reshape bones to restore function. This force is unyielding and can reshape bones to correct deformities, such as in clubfoot. Wolff's work challenges traditional theories of bone formation and emphasizes the functional adaptation of bones. It has significant implications for orthopedic surgery and the treatment of bone deformities. The book is well-structured, clear, and includes detailed illustrations. It is considered a landmark work in the field of bone biology and has had a lasting impact on medical science. The book also discusses the application of the transformation law to other areas of medicine and biology, including the theory of evolution and the mechanics of the body. It is a comprehensive and influential work that has shaped the understanding of bone biology and its clinical applications.Julius Wolff's "Das Gesetz der Transformation der Knochen" is a comprehensive work that summarizes a series of studies dating back to 1869. It is based on the mathematical insights of H. v. Meyer and the work of Culmann, who discovered the mathematical significance of bone architecture. Wolff introduced a new method using bone sections to study bone structure, leading to important discoveries such as the right-angle crossing of spongiosa trabeculae and the neutral axis of the femoral head. He proposed the "Transformation Law of Bones," which states that bone architecture changes in response to mechanical stress, and that these changes are governed by mathematical principles. Wolff also emphasized the importance of bone function in determining its shape, arguing that bone structure is determined by the mechanical load it bears. He introduced the concept of "Transformation Force," a therapeutic force that can reshape bones to restore function. This force is unyielding and can reshape bones to correct deformities, such as in clubfoot. Wolff's work challenges traditional theories of bone formation and emphasizes the functional adaptation of bones. It has significant implications for orthopedic surgery and the treatment of bone deformities. The book is well-structured, clear, and includes detailed illustrations. It is considered a landmark work in the field of bone biology and has had a lasting impact on medical science. The book also discusses the application of the transformation law to other areas of medicine and biology, including the theory of evolution and the mechanics of the body. It is a comprehensive and influential work that has shaped the understanding of bone biology and its clinical applications.