The study redefines overweight and obesity based on percent body fat (BF%) rather than body mass index (BMI). Current BMI thresholds for overweight and obesity are considered poor surrogates for actual adiposity. The study used data from 16,918 adults in the U.S. National Health and Nutrition Examination Survey (NHANES) to determine BF% thresholds for overweight and obesity based on metabolic syndrome (MetSyn) prevalence. For men, no cases of MetSyn were found below 18% BF, with MetSyn occurring at 25% BF for "overweight" and 30% BF for "obesity." For women, no cases of MetSyn were found below 30% BF, with MetSyn occurring at 36% BF for "overweight" and 42% BF for "obesity." These thresholds were compared to existing BMI thresholds, highlighting the variability in BMI's ability to predict BF%. The study concludes that practical methods for estimating body composition can replace BMI for obesity management, with clinically relevant thresholds for "overweight" and "obesity" defined as 25% and 36% BF for men and women, respectively, and 30% and 42% BF for men and women. The study emphasizes the importance of using direct measures of adiposity for managing obesity-related diseases.The study redefines overweight and obesity based on percent body fat (BF%) rather than body mass index (BMI). Current BMI thresholds for overweight and obesity are considered poor surrogates for actual adiposity. The study used data from 16,918 adults in the U.S. National Health and Nutrition Examination Survey (NHANES) to determine BF% thresholds for overweight and obesity based on metabolic syndrome (MetSyn) prevalence. For men, no cases of MetSyn were found below 18% BF, with MetSyn occurring at 25% BF for "overweight" and 30% BF for "obesity." For women, no cases of MetSyn were found below 30% BF, with MetSyn occurring at 36% BF for "overweight" and 42% BF for "obesity." These thresholds were compared to existing BMI thresholds, highlighting the variability in BMI's ability to predict BF%. The study concludes that practical methods for estimating body composition can replace BMI for obesity management, with clinically relevant thresholds for "overweight" and "obesity" defined as 25% and 36% BF for men and women, respectively, and 30% and 42% BF for men and women. The study emphasizes the importance of using direct measures of adiposity for managing obesity-related diseases.