November 20, 2001 | Gerald M. Edelman* and Joseph A. Gally
The article by Gerald M. Edelman and Joseph A. Gally explores the concept of degeneracy in biological systems, emphasizing its ubiquitous presence and its role in complexity. Degeneracy refers to the ability of structurally different elements to perform the same function or yield the same output, a property observed in genetic codes, immune systems, and various cellular and multicellular processes. The authors argue that degeneracy is not just a consequence of natural selection but is a prerequisite for it, as it allows for multiple genes to contribute to the same phenotypic feature. They provide examples from genetics, molecular biology, and neuroscience to illustrate how degeneracy enhances complexity and adaptability. The article also discusses the relationship between degeneracy and complexity, suggesting that high degeneracy systems tend to be more complex. Finally, the authors highlight the implications of degeneracy for human communication, technology, and evolutionary biology, emphasizing the need for further research to understand how degenerate systems become linked and synchronized across different levels of biological organization.The article by Gerald M. Edelman and Joseph A. Gally explores the concept of degeneracy in biological systems, emphasizing its ubiquitous presence and its role in complexity. Degeneracy refers to the ability of structurally different elements to perform the same function or yield the same output, a property observed in genetic codes, immune systems, and various cellular and multicellular processes. The authors argue that degeneracy is not just a consequence of natural selection but is a prerequisite for it, as it allows for multiple genes to contribute to the same phenotypic feature. They provide examples from genetics, molecular biology, and neuroscience to illustrate how degeneracy enhances complexity and adaptability. The article also discusses the relationship between degeneracy and complexity, suggesting that high degeneracy systems tend to be more complex. Finally, the authors highlight the implications of degeneracy for human communication, technology, and evolutionary biology, emphasizing the need for further research to understand how degenerate systems become linked and synchronized across different levels of biological organization.