This study investigates the association between dietary niacin intake and mortality risk among individuals with nonalcoholic fatty liver disease (NAFLD). Using data from the National Health and Nutrition Examination Survey (NHANES) from 2003 to 2018, the researchers analyzed 4315 adults with NAFLD. The study found that higher dietary niacin intake was associated with a lower risk of all-cause mortality, with a hazard ratio (HR) of 0.70 (95% CI, 0.50-0.96) compared to those with the lowest niacin intake. However, no significant association was found between niacin intake and cardiovascular disease (CVD) mortality. Stratified analyses revealed a significant interaction between niacin intake and diabetes, with higher niacin intake showing a stronger protective effect in non-diabetic participants. The study suggests that higher dietary niacin intake may reduce the risk of all-cause mortality in individuals with NAFLD, but further research is needed to confirm these findings and explore the mechanisms underlying this association.This study investigates the association between dietary niacin intake and mortality risk among individuals with nonalcoholic fatty liver disease (NAFLD). Using data from the National Health and Nutrition Examination Survey (NHANES) from 2003 to 2018, the researchers analyzed 4315 adults with NAFLD. The study found that higher dietary niacin intake was associated with a lower risk of all-cause mortality, with a hazard ratio (HR) of 0.70 (95% CI, 0.50-0.96) compared to those with the lowest niacin intake. However, no significant association was found between niacin intake and cardiovascular disease (CVD) mortality. Stratified analyses revealed a significant interaction between niacin intake and diabetes, with higher niacin intake showing a stronger protective effect in non-diabetic participants. The study suggests that higher dietary niacin intake may reduce the risk of all-cause mortality in individuals with NAFLD, but further research is needed to confirm these findings and explore the mechanisms underlying this association.