Disposition of Toxic Drugs and Chemicals in Man

Disposition of Toxic Drugs and Chemicals in Man

2002 | Randall C. Basel
This book, first published 25 years ago, is now available in its 6th updated and expanded edition. It provides comprehensive information on approximately 620 toxicologically relevant compounds, including pharmaceuticals, illegal drugs, alkaloids, plant protection agents, toxic metals, and frequently used chemicals and solvents. Each substance is described in a single to three-page chapter, following an alphabetical order of international synonyms or chemical names. The chapters include structural formulas, plasma half-life, distribution volume, and plasma protein binding. Additional sections cover occurrence and usage, blood concentrations, metabolism and excretion, toxicity, and analysis. The book is a valuable resource for clinical and forensic toxicology, offering detailed information on the clinical manifestations, poisoning dynamics, toxic and lethal doses, and concentrations of the compounds in various body fluids. It also includes methods for detection and quantification, though these may not be fully comprehensive or up-to-date. The book is well-organized and supported by extensive literature citations, making it a reliable reference for toxicologists and other professionals. This book, edited by Max Wichtl and published in its 4th extended and fully revised edition, provides detailed information on herbal medicines and their therapeutic uses. It is designed for pharmacists and physicians to address the growing trend of natural remedies. The book covers a wide range of plant products, including roots, leaves, and bark, and区分了“药物”和“毒品”的概念。It includes 205 monographs and seven short monographs on various drugs, each with a description of the plant source, content, and therapeutic indications. The book also discusses side effects, preparation methods, and identification techniques. It is a valuable resource for both professionals and personal use, providing insights into the benefits and limitations of herbal remedies. This traditional textbook, originally published in 1951, has been updated and expanded by Joachim Ströhle and Eberhard Schweda. It covers theoretical foundations, practical techniques, and detailed synthesis and analytical methods for various elements and compounds. The book emphasizes safety and protection in the laboratory and includes a comprehensive section on analytical chemistry. It is a valuable reference for both beginners and experienced chemists, offering practical guidance and historical context. While modern instrumental methods have reduced the practical value of some techniques, the book remains a useful resource for toxicological laboratories. This two-volume reference book, published by Helmut Hellwig and Hans-Hartwig Otto, is designed for physicians and pharmacists to aid in selecting and using medications. It covers approximately 1,500 medicinal substances across 38 chapters, organized by therapeutic categories. Each chapter provides detailed information on the disease, mechanisms of action, and pharmacokinetics of the substances. The book is highly current and includes a comprehensive register for easy reference. It is a valuable resource for clinical and forensic toxicologists, providing detailed information on the selection and evaluation of analytical findings.This book, first published 25 years ago, is now available in its 6th updated and expanded edition. It provides comprehensive information on approximately 620 toxicologically relevant compounds, including pharmaceuticals, illegal drugs, alkaloids, plant protection agents, toxic metals, and frequently used chemicals and solvents. Each substance is described in a single to three-page chapter, following an alphabetical order of international synonyms or chemical names. The chapters include structural formulas, plasma half-life, distribution volume, and plasma protein binding. Additional sections cover occurrence and usage, blood concentrations, metabolism and excretion, toxicity, and analysis. The book is a valuable resource for clinical and forensic toxicology, offering detailed information on the clinical manifestations, poisoning dynamics, toxic and lethal doses, and concentrations of the compounds in various body fluids. It also includes methods for detection and quantification, though these may not be fully comprehensive or up-to-date. The book is well-organized and supported by extensive literature citations, making it a reliable reference for toxicologists and other professionals. This book, edited by Max Wichtl and published in its 4th extended and fully revised edition, provides detailed information on herbal medicines and their therapeutic uses. It is designed for pharmacists and physicians to address the growing trend of natural remedies. The book covers a wide range of plant products, including roots, leaves, and bark, and区分了“药物”和“毒品”的概念。It includes 205 monographs and seven short monographs on various drugs, each with a description of the plant source, content, and therapeutic indications. The book also discusses side effects, preparation methods, and identification techniques. It is a valuable resource for both professionals and personal use, providing insights into the benefits and limitations of herbal remedies. This traditional textbook, originally published in 1951, has been updated and expanded by Joachim Ströhle and Eberhard Schweda. It covers theoretical foundations, practical techniques, and detailed synthesis and analytical methods for various elements and compounds. The book emphasizes safety and protection in the laboratory and includes a comprehensive section on analytical chemistry. It is a valuable reference for both beginners and experienced chemists, offering practical guidance and historical context. While modern instrumental methods have reduced the practical value of some techniques, the book remains a useful resource for toxicological laboratories. This two-volume reference book, published by Helmut Hellwig and Hans-Hartwig Otto, is designed for physicians and pharmacists to aid in selecting and using medications. It covers approximately 1,500 medicinal substances across 38 chapters, organized by therapeutic categories. Each chapter provides detailed information on the disease, mechanisms of action, and pharmacokinetics of the substances. The book is highly current and includes a comprehensive register for easy reference. It is a valuable resource for clinical and forensic toxicologists, providing detailed information on the selection and evaluation of analytical findings.
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