This study investigates the diversity and potential host interactions of viruses in deep-sea seamount sediments in the western Pacific Ocean. Using combined analyses of bulk metagenomes and viromes, the researchers found extensive viral diversity and previously unknown viral clades. Phylogenetic analyses and protein-sharing networks revealed extensive interactions between viruses and dominant prokaryote lineages, suggesting that viruses play significant roles in carbon, sulfur, and nitrogen cycling by compensating or augmenting host metabolisms. Temperate viruses are predicted to be prevalent in seamount sediments, which tend to carry auxiliary metabolic genes for host survivability. The geographical features of seamounts likely compromise the connectivity of viral communities, contributing to the high divergence of viral genetic spaces and populations across seamounts. Seamounts are globally distributed and form one of the major oceanic biomes. They are considered oases of biomass abundance and hotspots of species richness. Previous studies on seamount fauna have shown that seamounts have a diverse trophic architecture and tend to support aggregations of higher consumers, such as fish. However, the diversity and ecology of microbial communities in seamounts are much less understood. Over the past decades, significant efforts have been made to explore the diversity, function, and ecology of prokaryotes inhabiting seamount environments using metagenomics. Viruses are the most abundant and ubiquitous biological entities on Earth. They play major roles in marine ecosystems by controlling host abundance, influencing host diversity, and driving biogeochemical cycling. However, there are significant gaps in our knowledge regarding the community structure, genetic diversity, and ecological roles of viruses in seamount ecosystems. Only one publication has used epifluorescence microscopy to count virus-like particles in deep-sea sediments around seamounts. The results showed that benthic viral production was much higher in sediments around seamounts than in non-seamount sediments. Moreover, only one culturable virus has been isolated from seamount environments. In this study, high-depth sequencing and viral-sequence specific bioinformatics tools were used to explore the diversities, biogeography, and potential ecological roles of viruses in seamount ecosystems. The results show that seamount sediments are reservoirs of extremely diverse and previously unknown viruses. Extensive interactions between viruses and dominant prokaryote lineages, as well as the presence of abundant AMGs in virus genomes, highlight the central roles viruses play in shaping the structure and function of seamount microbiomes and in influencing the biogeochemical processes mediated by seamount microorganisms. Furthermore, the geographical features of seamounts likely compromise the connectivity of viral communities, highlighting the important role of the topography of the deep-sea landscape in shaping local viral communities. The study found that seamount viruses are diverse and novel, with a significant portion classified as members of the Caudoviricetes class. ssDNA viruses were also identified, including MicroThis study investigates the diversity and potential host interactions of viruses in deep-sea seamount sediments in the western Pacific Ocean. Using combined analyses of bulk metagenomes and viromes, the researchers found extensive viral diversity and previously unknown viral clades. Phylogenetic analyses and protein-sharing networks revealed extensive interactions between viruses and dominant prokaryote lineages, suggesting that viruses play significant roles in carbon, sulfur, and nitrogen cycling by compensating or augmenting host metabolisms. Temperate viruses are predicted to be prevalent in seamount sediments, which tend to carry auxiliary metabolic genes for host survivability. The geographical features of seamounts likely compromise the connectivity of viral communities, contributing to the high divergence of viral genetic spaces and populations across seamounts. Seamounts are globally distributed and form one of the major oceanic biomes. They are considered oases of biomass abundance and hotspots of species richness. Previous studies on seamount fauna have shown that seamounts have a diverse trophic architecture and tend to support aggregations of higher consumers, such as fish. However, the diversity and ecology of microbial communities in seamounts are much less understood. Over the past decades, significant efforts have been made to explore the diversity, function, and ecology of prokaryotes inhabiting seamount environments using metagenomics. Viruses are the most abundant and ubiquitous biological entities on Earth. They play major roles in marine ecosystems by controlling host abundance, influencing host diversity, and driving biogeochemical cycling. However, there are significant gaps in our knowledge regarding the community structure, genetic diversity, and ecological roles of viruses in seamount ecosystems. Only one publication has used epifluorescence microscopy to count virus-like particles in deep-sea sediments around seamounts. The results showed that benthic viral production was much higher in sediments around seamounts than in non-seamount sediments. Moreover, only one culturable virus has been isolated from seamount environments. In this study, high-depth sequencing and viral-sequence specific bioinformatics tools were used to explore the diversities, biogeography, and potential ecological roles of viruses in seamount ecosystems. The results show that seamount sediments are reservoirs of extremely diverse and previously unknown viruses. Extensive interactions between viruses and dominant prokaryote lineages, as well as the presence of abundant AMGs in virus genomes, highlight the central roles viruses play in shaping the structure and function of seamount microbiomes and in influencing the biogeochemical processes mediated by seamount microorganisms. Furthermore, the geographical features of seamounts likely compromise the connectivity of viral communities, highlighting the important role of the topography of the deep-sea landscape in shaping local viral communities. The study found that seamount viruses are diverse and novel, with a significant portion classified as members of the Caudoviricetes class. ssDNA viruses were also identified, including Micro