Drug treatment options for the 2019-new coronavirus (2019-nCoV)

Drug treatment options for the 2019-new coronavirus (2019-nCoV)

2020; 14(1):69-71. | Hongzhou Lu
As of January 22, 2020, 571 cases of the 2019-new coronavirus (2019-nCoV) had been reported in 25 provinces in China, with 95 severe cases and 17 deaths. There is currently no vaccine or antiviral treatment available for 2019-nCoV, making the identification of potential drug treatment options crucial. Three general methods are used to discover potential antiviral treatments: testing existing broad-spectrum antiviral drugs, screening chemical libraries, and developing new specific drugs based on genomic and biophysical understanding. Lopinavir/Ritonavir, nucleoside analogs, neuraminidase inhibitors, Remdesivir, peptide (EK1), arbidol, RNA synthesis inhibitors, anti-inflammatory drugs, and traditional Chinese medicine (such as ShuFengJieDu Capsules and Lianhuaqingwen Capsule) are potential drug treatment options. However, their efficacy and safety need to be confirmed through clinical experiments. The article highlights the importance of these drug discovery methods and the need for further research to determine the effectiveness of these treatments for 2019-nCoV.As of January 22, 2020, 571 cases of the 2019-new coronavirus (2019-nCoV) had been reported in 25 provinces in China, with 95 severe cases and 17 deaths. There is currently no vaccine or antiviral treatment available for 2019-nCoV, making the identification of potential drug treatment options crucial. Three general methods are used to discover potential antiviral treatments: testing existing broad-spectrum antiviral drugs, screening chemical libraries, and developing new specific drugs based on genomic and biophysical understanding. Lopinavir/Ritonavir, nucleoside analogs, neuraminidase inhibitors, Remdesivir, peptide (EK1), arbidol, RNA synthesis inhibitors, anti-inflammatory drugs, and traditional Chinese medicine (such as ShuFengJieDu Capsules and Lianhuaqingwen Capsule) are potential drug treatment options. However, their efficacy and safety need to be confirmed through clinical experiments. The article highlights the importance of these drug discovery methods and the need for further research to determine the effectiveness of these treatments for 2019-nCoV.
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Understanding Drug treatment options for the 2019-new coronavirus (2019-nCoV).