April 25, 2016 | Kazimer L. Skubi, Travis R. Blum, and Tehshik P. Yoon
This review discusses the application of dual-catalyst strategies in synthetic photochemistry, focusing on the cooperative interactions of photocatalysts with various cocatalysts such as redox mediators, Lewis and Bronsted acids, organocatalysts, enzymes, and transition metal complexes. The mechanisms of photocatalysis, including photoinduced electron transfer, hydrogen atom transfer, and energy transfer, are explored in detail. The review highlights the role of cocatalysts in enhancing the reactivity of photogenerated intermediates and their applications in a wide range of synthetic transformations. Key examples and mechanisms are provided to illustrate the effectiveness of these dual-catalyst systems in generating diverse reactive intermediates and facilitating complex organic synthesis.This review discusses the application of dual-catalyst strategies in synthetic photochemistry, focusing on the cooperative interactions of photocatalysts with various cocatalysts such as redox mediators, Lewis and Bronsted acids, organocatalysts, enzymes, and transition metal complexes. The mechanisms of photocatalysis, including photoinduced electron transfer, hydrogen atom transfer, and energy transfer, are explored in detail. The review highlights the role of cocatalysts in enhancing the reactivity of photogenerated intermediates and their applications in a wide range of synthetic transformations. Key examples and mechanisms are provided to illustrate the effectiveness of these dual-catalyst systems in generating diverse reactive intermediates and facilitating complex organic synthesis.