A durable Janus membrane with on-demand mode switching is fabricated using femtosecond laser technology. This membrane features hydrophilic micropores and microgrooves that enable unidirectional water flow in the stretching Janus mode. When released, the membrane enters a protection mode, closing the microchannels to resist mechanical abrasion and environmental contamination. The membrane demonstrates exceptional durability, withstanding 2000 cycles of mechanical abrasion and 10 days of air exposure, while maintaining its water transport function. The interconnected microgrooves enhance both the mechanical stability and water transport efficiency of the membrane. The Janus membrane is tested as a fog collector, showing its robustness in harsh environments. The design strategy offers new possibilities for applications in multiphase separation, fog harvesting, and wearable health-monitoring patches. The membrane's durability is achieved through a combination of surface roughness and chemical properties, with the protection mode ensuring the longevity of hydrophilic coatings. The study highlights the importance of addressing the durability issues of Janus membranes for practical applications in real-world environments. The membrane's ability to switch between Janus and protection modes provides a solution to common challenges in practical applications, such as coating degradation and clogging of microchannels. The results demonstrate the effectiveness of the mode switching strategy in enhancing the mechanical durability and functionality of Janus membranes. The membrane's performance is validated through various tests, including sandpaper abrasion, finger rubbing, and tape peeling, confirming its robustness. The study also investigates the water unidirectional penetration mechanism, revealing the role of microgrooves in enhancing transport efficiency. The Janus membrane's durability is further confirmed through thermal, humidity, and chemical stability tests, showing its potential for long-term use in harsh conditions. The research provides valuable insights for designing advanced durable fluid manipulation devices with wide-ranging applications.A durable Janus membrane with on-demand mode switching is fabricated using femtosecond laser technology. This membrane features hydrophilic micropores and microgrooves that enable unidirectional water flow in the stretching Janus mode. When released, the membrane enters a protection mode, closing the microchannels to resist mechanical abrasion and environmental contamination. The membrane demonstrates exceptional durability, withstanding 2000 cycles of mechanical abrasion and 10 days of air exposure, while maintaining its water transport function. The interconnected microgrooves enhance both the mechanical stability and water transport efficiency of the membrane. The Janus membrane is tested as a fog collector, showing its robustness in harsh environments. The design strategy offers new possibilities for applications in multiphase separation, fog harvesting, and wearable health-monitoring patches. The membrane's durability is achieved through a combination of surface roughness and chemical properties, with the protection mode ensuring the longevity of hydrophilic coatings. The study highlights the importance of addressing the durability issues of Janus membranes for practical applications in real-world environments. The membrane's ability to switch between Janus and protection modes provides a solution to common challenges in practical applications, such as coating degradation and clogging of microchannels. The results demonstrate the effectiveness of the mode switching strategy in enhancing the mechanical durability and functionality of Janus membranes. The membrane's performance is validated through various tests, including sandpaper abrasion, finger rubbing, and tape peeling, confirming its robustness. The study also investigates the water unidirectional penetration mechanism, revealing the role of microgrooves in enhancing transport efficiency. The Janus membrane's durability is further confirmed through thermal, humidity, and chemical stability tests, showing its potential for long-term use in harsh conditions. The research provides valuable insights for designing advanced durable fluid manipulation devices with wide-ranging applications.