This paper examines the effectiveness of IT project management in healthcare digitalization, exploring current practices, challenges, and future trends. It begins by analyzing the healthcare digitalization landscape, emphasizing the critical role of IT project management in orchestrating technological transformations. A comprehensive literature review provides insights into key concepts, models, and success metrics. Challenges such as interoperability, resistance to change, and data security are scrutinized alongside strategic solutions. The paper outlines best practices, emphasizing stakeholder collaboration, agile methodologies, and continuous evaluation. Future trends, including AI integration and blockchain, are discussed, offering a forward-looking perspective. The research highlights the essential dynamics of IT project management in healthcare, providing a roadmap for effective digitalization in the evolving healthcare landscape. Keywords: Healthcare Digitalization, IT Project Management, Stakeholder Collaboration, Interoperability. The paper explores the intersection of IT and healthcare, highlighting the transformative role of digitalization in enhancing patient care, streamlining operations, and improving health outcomes. It discusses the importance of effective project management in overseeing digitalization efforts, emphasizing the need for flexibility, adaptability, and stakeholder engagement. The paper also addresses challenges such as interoperability, data security, and resistance to change, along with opportunities like AI, blockchain, and telemedicine. It emphasizes the need for robust cybersecurity measures, effective change management, and the integration of emerging technologies. The study concludes that successful healthcare digitalization requires a strategic approach, aligning IT projects with organizational goals and fostering collaboration among stakeholders. The effectiveness of IT project management in healthcare digitalization is influenced by factors such as organizational culture, stakeholder engagement, resource allocation, regulatory compliance, and change management. The paper proposes solutions to address challenges, including standardizing interoperability, implementing effective change management strategies, and prioritizing data security. It also discusses success metrics and evaluation strategies to ensure project effectiveness. Future trends such as AI, blockchain, telehealth, IoT, and enhanced cybersecurity are anticipated to shape the landscape of healthcare IT project management. Best practices, including comprehensive planning, stakeholder collaboration, agile methodologies, and a commitment to data security, are emphasized as guiding principles. The conclusion underscores the importance of IT project management in driving successful healthcare digitalization, ensuring alignment with organizational objectives, and improving patient outcomes.This paper examines the effectiveness of IT project management in healthcare digitalization, exploring current practices, challenges, and future trends. It begins by analyzing the healthcare digitalization landscape, emphasizing the critical role of IT project management in orchestrating technological transformations. A comprehensive literature review provides insights into key concepts, models, and success metrics. Challenges such as interoperability, resistance to change, and data security are scrutinized alongside strategic solutions. The paper outlines best practices, emphasizing stakeholder collaboration, agile methodologies, and continuous evaluation. Future trends, including AI integration and blockchain, are discussed, offering a forward-looking perspective. The research highlights the essential dynamics of IT project management in healthcare, providing a roadmap for effective digitalization in the evolving healthcare landscape. Keywords: Healthcare Digitalization, IT Project Management, Stakeholder Collaboration, Interoperability. The paper explores the intersection of IT and healthcare, highlighting the transformative role of digitalization in enhancing patient care, streamlining operations, and improving health outcomes. It discusses the importance of effective project management in overseeing digitalization efforts, emphasizing the need for flexibility, adaptability, and stakeholder engagement. The paper also addresses challenges such as interoperability, data security, and resistance to change, along with opportunities like AI, blockchain, and telemedicine. It emphasizes the need for robust cybersecurity measures, effective change management, and the integration of emerging technologies. The study concludes that successful healthcare digitalization requires a strategic approach, aligning IT projects with organizational goals and fostering collaboration among stakeholders. The effectiveness of IT project management in healthcare digitalization is influenced by factors such as organizational culture, stakeholder engagement, resource allocation, regulatory compliance, and change management. The paper proposes solutions to address challenges, including standardizing interoperability, implementing effective change management strategies, and prioritizing data security. It also discusses success metrics and evaluation strategies to ensure project effectiveness. Future trends such as AI, blockchain, telehealth, IoT, and enhanced cybersecurity are anticipated to shape the landscape of healthcare IT project management. Best practices, including comprehensive planning, stakeholder collaboration, agile methodologies, and a commitment to data security, are emphasized as guiding principles. The conclusion underscores the importance of IT project management in driving successful healthcare digitalization, ensuring alignment with organizational objectives, and improving patient outcomes.