The article reviews the advancements in electrospun wound dressings and hydrogels used for wound healing, focusing on their formation, application, and functionalization. Traditional wound dressings, such as gauze and bandages, have limitations in managing complex wounds and promoting healing. Electrospun nanofibers and hydrogels with incorporated antibacterial compounds offer promising solutions by mimicking the extracellular collagen matrix (ECM) and providing targeted drug delivery. The review highlights the unique properties of electrospun materials, including high surface-to-volume ratios, porosity, and the ability to facilitate cell attachment and nutrient exchange. Recent studies have demonstrated the effectiveness of these materials in treating various types of wounds, including chronic and infected wounds, by promoting angiogenesis, tissue regeneration, and reducing scar formation. The article also discusses the challenges and future prospects in the development of advanced wound dressings, emphasizing the importance of materials that are elastic, biocompatible, and biodegradable. Additionally, it explores the integration of antibacterial agents, such as nanoparticles and antimicrobial peptides, into these materials to enhance their therapeutic efficacy. The review concludes by highlighting the potential of thermoresponsive hydrogels as dynamic and antibacterial wound dressings, which can adapt to different wound conditions and provide sustained drug release.The article reviews the advancements in electrospun wound dressings and hydrogels used for wound healing, focusing on their formation, application, and functionalization. Traditional wound dressings, such as gauze and bandages, have limitations in managing complex wounds and promoting healing. Electrospun nanofibers and hydrogels with incorporated antibacterial compounds offer promising solutions by mimicking the extracellular collagen matrix (ECM) and providing targeted drug delivery. The review highlights the unique properties of electrospun materials, including high surface-to-volume ratios, porosity, and the ability to facilitate cell attachment and nutrient exchange. Recent studies have demonstrated the effectiveness of these materials in treating various types of wounds, including chronic and infected wounds, by promoting angiogenesis, tissue regeneration, and reducing scar formation. The article also discusses the challenges and future prospects in the development of advanced wound dressings, emphasizing the importance of materials that are elastic, biocompatible, and biodegradable. Additionally, it explores the integration of antibacterial agents, such as nanoparticles and antimicrobial peptides, into these materials to enhance their therapeutic efficacy. The review concludes by highlighting the potential of thermoresponsive hydrogels as dynamic and antibacterial wound dressings, which can adapt to different wound conditions and provide sustained drug release.