Emerging pathogenic links between microbiota and the gut-lung axis

Emerging pathogenic links between microbiota and the gut-lung axis

| Kurtis F. Budden, Shaan L. Gellatly, David L.A. Wood, Matthew A. Cooper, Mark Morrison, Philip Hugenholtz, Philip M. Hansbro
The article reviews the emerging links between the gut microbiota and the lung, highlighting the gut-lung axis and its potential role in disease development. It discusses how changes in the gut microbiota, known as dysbiosis, can influence immune responses and contribute to lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). The authors emphasize the importance of understanding the interactions between the gut and lung microbiota, and how these interactions can be manipulated to treat respiratory diseases. They also explore the impact of specific microbial species and metabolites on host immunity, and the potential therapeutic interventions that could benefit from these findings. The article concludes by emphasizing the need for further research to fully understand the gut-lung axis and develop effective treatments.The article reviews the emerging links between the gut microbiota and the lung, highlighting the gut-lung axis and its potential role in disease development. It discusses how changes in the gut microbiota, known as dysbiosis, can influence immune responses and contribute to lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). The authors emphasize the importance of understanding the interactions between the gut and lung microbiota, and how these interactions can be manipulated to treat respiratory diseases. They also explore the impact of specific microbial species and metabolites on host immunity, and the potential therapeutic interventions that could benefit from these findings. The article concludes by emphasizing the need for further research to fully understand the gut-lung axis and develop effective treatments.
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