This review summarizes recent advances in chiral inorganic nanomaterials for enantioselective catalysis. Asymmetric transformations and synthesis have gained significant attention due to the demand for chiral compounds in various industries. Chiral inorganic nanocatalysts have emerged as a promising area, offering high efficiency, recyclability, and structural stability. These catalysts are constructed using chiral ligands, metal complexes, biological catalysts, and small organic molecules. Chiral inorganic nanocatalysts exhibit remarkable enantioselectivity and are applied in chiral organic synthesis, enantioselective transformations, cleavage of chiral macromolecules, and coupling of chiral small molecules. Chiral metal nanocatalysts are synthesized using various methods, including chiral molecule-guided synthesis, post-modification, and chiral templates. These catalysts show high enantioselectivity and are used in reactions such as asymmetric 1,4-addition. Chiral metal oxide nanocatalysts, like those based on metal oxides, are effective in electrochemical and redox reactions. They are synthesized using methods such as sol-gel, hydrothermal, and precipitation. These catalysts are known for their active, selective, and energy-efficient properties. Chiral semiconductor nanocatalysts, such as chiral CdTe and Cu1.96S nanoparticles, are used for photocatalytic reactions and DNA cleavage. These materials exhibit high enantioselectivity and are applied in various biological and chemical processes. Chiral composite inorganic nanomaterials combine different constituents to enhance catalytic performance. Challenges include controlling stereochemistry, dimensional mismatch, and redox properties. Future research aims to develop more efficient and versatile chiral nanocatalysts with improved enantioselectivity and catalytic efficiency. The field holds promise for revolutionizing catalysis and applications in various scientific areas.This review summarizes recent advances in chiral inorganic nanomaterials for enantioselective catalysis. Asymmetric transformations and synthesis have gained significant attention due to the demand for chiral compounds in various industries. Chiral inorganic nanocatalysts have emerged as a promising area, offering high efficiency, recyclability, and structural stability. These catalysts are constructed using chiral ligands, metal complexes, biological catalysts, and small organic molecules. Chiral inorganic nanocatalysts exhibit remarkable enantioselectivity and are applied in chiral organic synthesis, enantioselective transformations, cleavage of chiral macromolecules, and coupling of chiral small molecules. Chiral metal nanocatalysts are synthesized using various methods, including chiral molecule-guided synthesis, post-modification, and chiral templates. These catalysts show high enantioselectivity and are used in reactions such as asymmetric 1,4-addition. Chiral metal oxide nanocatalysts, like those based on metal oxides, are effective in electrochemical and redox reactions. They are synthesized using methods such as sol-gel, hydrothermal, and precipitation. These catalysts are known for their active, selective, and energy-efficient properties. Chiral semiconductor nanocatalysts, such as chiral CdTe and Cu1.96S nanoparticles, are used for photocatalytic reactions and DNA cleavage. These materials exhibit high enantioselectivity and are applied in various biological and chemical processes. Chiral composite inorganic nanomaterials combine different constituents to enhance catalytic performance. Challenges include controlling stereochemistry, dimensional mismatch, and redox properties. Future research aims to develop more efficient and versatile chiral nanocatalysts with improved enantioselectivity and catalytic efficiency. The field holds promise for revolutionizing catalysis and applications in various scientific areas.