The article reviews the latest advancements in chiral inorganic nanomaterials for enantioselective catalysis, highlighting their significance in asymmetric transformations and synthesis. Chiral inorganic nanocatalysts have emerged as a highly innovative research area, offering significant improvements in catalytic efficiency, recyclability, and structural stability compared to traditional chiral organic catalysts. The review covers various methods for synthesizing these nanomaterials, including the combination of achiral inorganic nanoparticles with chiral organic catalysts, the use of chiral metal complexes, and the integration of biological catalysts. Key advancements include the development of chiral metal nanocatalysts, chiral metal oxide nanocatalysts, and chiral semiconductor nanocatalysts, each with unique properties and applications. The article also discusses the challenges in achieving high enantioselectivity and the potential solutions, such as optimizing synthetic pathways, controlling the size and configuration of chiral recognition centers, and enhancing the catalytic efficiency of nanomaterials. Finally, the review concludes by emphasizing the potential of chiral inorganic nanomaterials to revolutionize various fields, including biological systems, agriculture, biomedical science, and environmental science.The article reviews the latest advancements in chiral inorganic nanomaterials for enantioselective catalysis, highlighting their significance in asymmetric transformations and synthesis. Chiral inorganic nanocatalysts have emerged as a highly innovative research area, offering significant improvements in catalytic efficiency, recyclability, and structural stability compared to traditional chiral organic catalysts. The review covers various methods for synthesizing these nanomaterials, including the combination of achiral inorganic nanoparticles with chiral organic catalysts, the use of chiral metal complexes, and the integration of biological catalysts. Key advancements include the development of chiral metal nanocatalysts, chiral metal oxide nanocatalysts, and chiral semiconductor nanocatalysts, each with unique properties and applications. The article also discusses the challenges in achieving high enantioselectivity and the potential solutions, such as optimizing synthetic pathways, controlling the size and configuration of chiral recognition centers, and enhancing the catalytic efficiency of nanomaterials. Finally, the review concludes by emphasizing the potential of chiral inorganic nanomaterials to revolutionize various fields, including biological systems, agriculture, biomedical science, and environmental science.