This Perspective discusses the development and challenges of electrochemically mediated carbon dioxide (CO₂) capture systems, emphasizing the importance of engineering approaches to enhance their performance for widespread implementation. With increasing atmospheric CO₂ concentrations and the need to limit global warming to below 1.5°C, there is a pressing need for low-cost, scalable, and low-energy CO₂ separation technologies. Electrochemically mediated carbon capture (EMCC) offers advantages such as low energy consumption, direct integration with renewable energy sources, and modular scalability. EMCC systems modulate CO₂ sorption capacity through applied potential, using redox-active species to drive pH changes or react with CO₂. However, challenges such as energy penalties from redox-active species transport, gas transport, and bubble formation limit volumetric productivity and scaling potential. The article highlights the importance of addressing these challenges to enable cost-competitive EMCC systems. The article reviews various EMCC configurations, including direct, semi-direct, and indirect cycles, and discusses their thermodynamic and process characteristics. It also explores the impact of redox-active species on CO₂ sorption and the challenges of implementing these systems in real-world conditions. The study emphasizes the need for efficient electrochemical processes, including the optimization of current density, Faradaic efficiency, and specific energy consumption. It also addresses the challenges of bubble formation, which can significantly impact system performance by blocking electrode areas and increasing ohmic losses. Strategies for managing bubbles, such as surfactants, hollow fibers, and gas-diffusion electrodes, are discussed. The article also examines the economic and scaling considerations of EMCC systems, highlighting the importance of identifying key performance metrics and cost factors. It discusses the potential of EMCC systems in retrofitting existing CO₂ capture infrastructure and their application in distributed direct air capture. The study concludes that further research is needed to optimize EMCC systems, improve mass transfer, and reduce energy consumption, enabling their widespread implementation for carbon capture and storage.This Perspective discusses the development and challenges of electrochemically mediated carbon dioxide (CO₂) capture systems, emphasizing the importance of engineering approaches to enhance their performance for widespread implementation. With increasing atmospheric CO₂ concentrations and the need to limit global warming to below 1.5°C, there is a pressing need for low-cost, scalable, and low-energy CO₂ separation technologies. Electrochemically mediated carbon capture (EMCC) offers advantages such as low energy consumption, direct integration with renewable energy sources, and modular scalability. EMCC systems modulate CO₂ sorption capacity through applied potential, using redox-active species to drive pH changes or react with CO₂. However, challenges such as energy penalties from redox-active species transport, gas transport, and bubble formation limit volumetric productivity and scaling potential. The article highlights the importance of addressing these challenges to enable cost-competitive EMCC systems. The article reviews various EMCC configurations, including direct, semi-direct, and indirect cycles, and discusses their thermodynamic and process characteristics. It also explores the impact of redox-active species on CO₂ sorption and the challenges of implementing these systems in real-world conditions. The study emphasizes the need for efficient electrochemical processes, including the optimization of current density, Faradaic efficiency, and specific energy consumption. It also addresses the challenges of bubble formation, which can significantly impact system performance by blocking electrode areas and increasing ohmic losses. Strategies for managing bubbles, such as surfactants, hollow fibers, and gas-diffusion electrodes, are discussed. The article also examines the economic and scaling considerations of EMCC systems, highlighting the importance of identifying key performance metrics and cost factors. It discusses the potential of EMCC systems in retrofitting existing CO₂ capture infrastructure and their application in distributed direct air capture. The study concludes that further research is needed to optimize EMCC systems, improve mass transfer, and reduce energy consumption, enabling their widespread implementation for carbon capture and storage.