This review aims to summarize the incidence, prevalence, trends in mortality, and general prognosis of coronary heart disease (CHD) and acute coronary syndrome (ACS). Despite a gradual decline in CHD mortality in western countries, it still accounts for about one-third of all deaths in individuals over 35 years old. The mortality from CHD is expected to increase in developing countries, highlighting the need for effective primary prevention strategies and identifying risk groups and areas for improvement. The article discusses the epidemiology of CHD and ACS, including the relationship between sudden cardiac death (SCD) and CHD, and provides insights into the impact of various risk factors and the effectiveness of preventive measures.This review aims to summarize the incidence, prevalence, trends in mortality, and general prognosis of coronary heart disease (CHD) and acute coronary syndrome (ACS). Despite a gradual decline in CHD mortality in western countries, it still accounts for about one-third of all deaths in individuals over 35 years old. The mortality from CHD is expected to increase in developing countries, highlighting the need for effective primary prevention strategies and identifying risk groups and areas for improvement. The article discusses the epidemiology of CHD and ACS, including the relationship between sudden cardiac death (SCD) and CHD, and provides insights into the impact of various risk factors and the effectiveness of preventive measures.