The book "Essentials of Glycobiology," edited by Varki, Cummings, Esko, Freeze, Stanley, Bertozzi, Hart, and Etzler, is a comprehensive resource in the field of glycobiology. It covers significant advancements in the discipline over the past decade and is dedicated to the memory of pioneers Rosalind Kornfeld and Roger Jeanloz. The book consists of 51 chapters, a glossary, a study guide, and a subject index. The content is divided into six parts: 1. **General Principles**: Discusses the historical background, major subjects, and cellular organization of glycosylation. 2. **Structure and Biosynthesis of Glycans**: Focuses on the structure and biosynthesis of various types of glycans. 3. **Organismal Diversity**: Explores the evolution of glycan diversity in different organisms. 4. **Glycan-Binding Proteins**: Covers the history, classification, and types of lectins and other glycan-binding proteins. 5. **Role of Glycans in Physiology and Disease**: Examines the physiological and pathological roles of glycans, including their involvement in infections, genetic disorders, and cancer. 6. **Methods and Applications**: Analyzes methods for studying glycans, including antibody and lectin applications, chemical synthesis, and biotechnological uses. Each chapter includes a list of references, and the book also features a study guide with thought-provoking questions, a dictionary of terms, and a subject index. It is valuable for both beginners and experts in glycobiology, as well as for biochemists, molecular biologists, biotechnologists, and physicians.The book "Essentials of Glycobiology," edited by Varki, Cummings, Esko, Freeze, Stanley, Bertozzi, Hart, and Etzler, is a comprehensive resource in the field of glycobiology. It covers significant advancements in the discipline over the past decade and is dedicated to the memory of pioneers Rosalind Kornfeld and Roger Jeanloz. The book consists of 51 chapters, a glossary, a study guide, and a subject index. The content is divided into six parts: 1. **General Principles**: Discusses the historical background, major subjects, and cellular organization of glycosylation. 2. **Structure and Biosynthesis of Glycans**: Focuses on the structure and biosynthesis of various types of glycans. 3. **Organismal Diversity**: Explores the evolution of glycan diversity in different organisms. 4. **Glycan-Binding Proteins**: Covers the history, classification, and types of lectins and other glycan-binding proteins. 5. **Role of Glycans in Physiology and Disease**: Examines the physiological and pathological roles of glycans, including their involvement in infections, genetic disorders, and cancer. 6. **Methods and Applications**: Analyzes methods for studying glycans, including antibody and lectin applications, chemical synthesis, and biotechnological uses. Each chapter includes a list of references, and the book also features a study guide with thought-provoking questions, a dictionary of terms, and a subject index. It is valuable for both beginners and experts in glycobiology, as well as for biochemists, molecular biologists, biotechnologists, and physicians.