The European Respiratory Society (ERS) has published guidelines for the management of adult bronchiectasis, addressing key clinical questions through a systematic literature review. The guidelines aim to improve the quality of care and outcomes for patients with bronchiectasis. The recommendations cover investigation of underlying causes, treatment of exacerbations, pathogen eradication, long-term antibiotic treatment, anti-inflammatory agents, mucoactive drugs, bronchodilators, surgical treatment, and respiratory physiotherapy. The guidelines are based on the GRADE approach, which assesses the quality of evidence and the strength of recommendations. Key recommendations include standardized testing for the cause of bronchiectasis, 14-21 days of systemic antibiotic therapy for acute exacerbations, eradication treatment for *Pseudomonas aeruginosa*, and long-term antibiotic and mucoactive treatments for specific patient groups. The guidelines also emphasize the importance of considering individual patient circumstances and values when making treatment decisions.The European Respiratory Society (ERS) has published guidelines for the management of adult bronchiectasis, addressing key clinical questions through a systematic literature review. The guidelines aim to improve the quality of care and outcomes for patients with bronchiectasis. The recommendations cover investigation of underlying causes, treatment of exacerbations, pathogen eradication, long-term antibiotic treatment, anti-inflammatory agents, mucoactive drugs, bronchodilators, surgical treatment, and respiratory physiotherapy. The guidelines are based on the GRADE approach, which assesses the quality of evidence and the strength of recommendations. Key recommendations include standardized testing for the cause of bronchiectasis, 14-21 days of systemic antibiotic therapy for acute exacerbations, eradication treatment for *Pseudomonas aeruginosa*, and long-term antibiotic and mucoactive treatments for specific patient groups. The guidelines also emphasize the importance of considering individual patient circumstances and values when making treatment decisions.