This review critically examines evidence-based psychosocial interventions for Schizophrenia Spectrum Disorders (SSD), aiming to provide an overview of their effectiveness and implementation. SSD are severe conditions characterized by cognitive impairments, poor social skills, and reduced psychosocial functioning. While pharmacological treatments are effective in managing psychotic symptoms, they often fall short in improving real-world outcomes such as cognitive performance, social skills, and quality of life. Psychosocial interventions, therefore, play a crucial role in enhancing these outcomes. Recent systematic reviews and meta-analyses have provided detailed insights into the acceptability, effectiveness, and moderators of response for various psychosocial interventions. Individual studies have also contributed novel findings on their implementation and combination in rehabilitation practices. Cognitive remediation, metacognitive training, social skills training, psychoeducation, family interventions, cognitive behavioral therapy, physical exercise, lifestyle interventions, supported employment, and other interventions are considered evidence-based treatments for SSD. These interventions can be particularly useful in early intervention services, where they can complement pharmacological treatments and address specific needs. Psychosocial interventions can significantly improve cognitive performance, social skills, and real-world functioning. Future research should focus on developing newer interventions, understanding barriers and facilitators to implementation, and exploring the potential of novel technologies such as telemedicine and virtual reality. Early intervention services, in particular, offer a promising approach to improving outcomes for individuals with SSD.This review critically examines evidence-based psychosocial interventions for Schizophrenia Spectrum Disorders (SSD), aiming to provide an overview of their effectiveness and implementation. SSD are severe conditions characterized by cognitive impairments, poor social skills, and reduced psychosocial functioning. While pharmacological treatments are effective in managing psychotic symptoms, they often fall short in improving real-world outcomes such as cognitive performance, social skills, and quality of life. Psychosocial interventions, therefore, play a crucial role in enhancing these outcomes. Recent systematic reviews and meta-analyses have provided detailed insights into the acceptability, effectiveness, and moderators of response for various psychosocial interventions. Individual studies have also contributed novel findings on their implementation and combination in rehabilitation practices. Cognitive remediation, metacognitive training, social skills training, psychoeducation, family interventions, cognitive behavioral therapy, physical exercise, lifestyle interventions, supported employment, and other interventions are considered evidence-based treatments for SSD. These interventions can be particularly useful in early intervention services, where they can complement pharmacological treatments and address specific needs. Psychosocial interventions can significantly improve cognitive performance, social skills, and real-world functioning. Future research should focus on developing newer interventions, understanding barriers and facilitators to implementation, and exploring the potential of novel technologies such as telemedicine and virtual reality. Early intervention services, in particular, offer a promising approach to improving outcomes for individuals with SSD.