This study provides a detailed quantification and characterization of ocean plastic within the Great Pacific Garbage Patch (GPGP), a major hotspot of oceanic plastic pollution. The GPGP, located between California and Hawaii, is characterized by high concentrations of plastic debris, primarily composed of polyethylene (PE) and polypropylene (PP) pieces. The study combines data from multi-vessel and aircraft surveys to estimate that the GPGP contains approximately 79,000 tonnes of plastic, spread across an area of 1.6 million square kilometers. This figure is significantly higher than previously reported estimates, attributed to more robust methods for quantifying larger debris. Over three-quarters of the GPGP mass is carried by debris larger than 5 cm, with fishing nets comprising at least 46% of the total. Microplastics, while accounting for only 8% of the total mass, make up 94% of the estimated 1.8 trillion pieces in the area. The study also highlights the exponential increase in plastic concentrations within the GPGP over the last decades, suggesting that ocean plastic pollution is increasing at a faster rate than in surrounding waters. The results emphasize the need for better quantification and mitigation of plastic inputs from marine industries, such as fishing, aquaculture, and shipping, to address this critical environmental issue.This study provides a detailed quantification and characterization of ocean plastic within the Great Pacific Garbage Patch (GPGP), a major hotspot of oceanic plastic pollution. The GPGP, located between California and Hawaii, is characterized by high concentrations of plastic debris, primarily composed of polyethylene (PE) and polypropylene (PP) pieces. The study combines data from multi-vessel and aircraft surveys to estimate that the GPGP contains approximately 79,000 tonnes of plastic, spread across an area of 1.6 million square kilometers. This figure is significantly higher than previously reported estimates, attributed to more robust methods for quantifying larger debris. Over three-quarters of the GPGP mass is carried by debris larger than 5 cm, with fishing nets comprising at least 46% of the total. Microplastics, while accounting for only 8% of the total mass, make up 94% of the estimated 1.8 trillion pieces in the area. The study also highlights the exponential increase in plastic concentrations within the GPGP over the last decades, suggesting that ocean plastic pollution is increasing at a faster rate than in surrounding waters. The results emphasize the need for better quantification and mitigation of plastic inputs from marine industries, such as fishing, aquaculture, and shipping, to address this critical environmental issue.