ExPASy is a proteomics server offering a variety of databases and analysis tools for protein research. It is maintained by the Swiss Institute of Bioinformatics (SIB) and provides access to databases such as SWISS-PROT, TrEMBL, SWISS-2DPAGE, PROSITE, ENZYME, and the SWISS-MODEL repository. These databases are tightly integrated, with SWISS-PROT serving as a central hub for proteomics data. ExPASy also offers a range of analysis tools for tasks such as sequence alignment, post-translational modification prediction, and protein structure analysis. The server emphasizes integration with other resources and provides both explicit and implicit cross-references to enhance database interoperability. ExPASy started in 1993 and has mirror sites in various countries to improve access. The server is free for academic users, while commercial users pay an annual subscription fee. ExPASy provides a wide range of software tools for sequence analysis and proteomics, including BLAST, ScanProsite, SWISS-MODEL, and others. It also offers a variety of tools for protein identification and analysis, such as PeptIdent, TagIdent, and MultiIdent. ExPASy serves as a portal to other life science resources, offering links to various tools and databases. The server is continuously updated and provides detailed documentation and user support. ExPASy is a valuable resource for researchers in the field of proteomics and bioinformatics.ExPASy is a proteomics server offering a variety of databases and analysis tools for protein research. It is maintained by the Swiss Institute of Bioinformatics (SIB) and provides access to databases such as SWISS-PROT, TrEMBL, SWISS-2DPAGE, PROSITE, ENZYME, and the SWISS-MODEL repository. These databases are tightly integrated, with SWISS-PROT serving as a central hub for proteomics data. ExPASy also offers a range of analysis tools for tasks such as sequence alignment, post-translational modification prediction, and protein structure analysis. The server emphasizes integration with other resources and provides both explicit and implicit cross-references to enhance database interoperability. ExPASy started in 1993 and has mirror sites in various countries to improve access. The server is free for academic users, while commercial users pay an annual subscription fee. ExPASy provides a wide range of software tools for sequence analysis and proteomics, including BLAST, ScanProsite, SWISS-MODEL, and others. It also offers a variety of tools for protein identification and analysis, such as PeptIdent, TagIdent, and MultiIdent. ExPASy serves as a portal to other life science resources, offering links to various tools and databases. The server is continuously updated and provides detailed documentation and user support. ExPASy is a valuable resource for researchers in the field of proteomics and bioinformatics.