The monograph "Excitation-Contraction Coupling and Cardiac Contractile Force" by Donald M. Bers provides an overview of calcium regulation in cardiac muscle cells, focusing on excitation-contraction coupling and the control of cardiac contractile force. The book aims to be accessible to students and researchers in various disciplines related to cardiovascular and muscle systems. It integrates recent molecular investigations and presents new findings alongside established knowledge, offering a comprehensive and up-to-date resource. Key topics include the structure and function of major cellular components involved in excitation-contraction coupling, the sources and sinks of activator calcium, the properties of sarcolemmal calcium channels, the role of Na/Ca exchange, and the mechanisms of cardiac inotropy and calcium overload. The book also discusses species differences and the impact of various physiological and pathological conditions on cardiac function.The monograph "Excitation-Contraction Coupling and Cardiac Contractile Force" by Donald M. Bers provides an overview of calcium regulation in cardiac muscle cells, focusing on excitation-contraction coupling and the control of cardiac contractile force. The book aims to be accessible to students and researchers in various disciplines related to cardiovascular and muscle systems. It integrates recent molecular investigations and presents new findings alongside established knowledge, offering a comprehensive and up-to-date resource. Key topics include the structure and function of major cellular components involved in excitation-contraction coupling, the sources and sinks of activator calcium, the properties of sarcolemmal calcium channels, the role of Na/Ca exchange, and the mechanisms of cardiac inotropy and calcium overload. The book also discusses species differences and the impact of various physiological and pathological conditions on cardiac function.