This paper presents a systematic analysis of large momentum transfer exclusive processes in perturbative Quantum Chromodynamics (QCD). The authors derive predictions for the scaling behavior, angular dependence, helicity structure, and normalization of elastic and inelastic form factors, as well as large angle exclusive scattering amplitudes for hadrons and photons. They prove that these reactions are dominated by quark and gluon subprocesses at short distances, leading to rigorous predictions of QCD for the power-law fall-off of these amplitudes with momentum transfer. The analysis is carried out systematically in powers of the running coupling constant \(\alpha_s(Q^2)\), using light-cone perturbation theory and the light-cone gauge. The distribution amplitude \(\phi(x_1, Q)\) is shown to be process-independent and evolves according to an equation that includes the effects of hadronic wave functions at short distances. The paper also discusses the role of non-valence Fock states and the suppression of endpoint contributions to form factors. Detailed applications to hadronic form factors and predictions for large angle exclusive reactions are provided, along with a discussion of future prospects.This paper presents a systematic analysis of large momentum transfer exclusive processes in perturbative Quantum Chromodynamics (QCD). The authors derive predictions for the scaling behavior, angular dependence, helicity structure, and normalization of elastic and inelastic form factors, as well as large angle exclusive scattering amplitudes for hadrons and photons. They prove that these reactions are dominated by quark and gluon subprocesses at short distances, leading to rigorous predictions of QCD for the power-law fall-off of these amplitudes with momentum transfer. The analysis is carried out systematically in powers of the running coupling constant \(\alpha_s(Q^2)\), using light-cone perturbation theory and the light-cone gauge. The distribution amplitude \(\phi(x_1, Q)\) is shown to be process-independent and evolves according to an equation that includes the effects of hadronic wave functions at short distances. The paper also discusses the role of non-valence Fock states and the suppression of endpoint contributions to form factors. Detailed applications to hadronic form factors and predictions for large angle exclusive reactions are provided, along with a discussion of future prospects.