Exercise-based rehabilitation for coronary heart disease (Review) by Jolliffe J, Rees K, Taylor RRS, Thompson DR, Oldridge N, Ebrahim S. This Cochrane review evaluates the effectiveness of exercise-based rehabilitation compared to usual care and comprehensive cardiac rehabilitation in reducing mortality, morbidity, and modifiable cardiac risk factors in patients with coronary heart disease. The review analyzed 8440 patients across 51 studies, with 36 trials of exercise-based rehabilitation and 16 trials of comprehensive rehabilitation. The results showed a 27% reduction in all-cause mortality for exercise-only rehabilitation and a 13% reduction for comprehensive rehabilitation. Total cardiac mortality was reduced by 31% and 26% respectively. Comprehensive rehabilitation also led to significant reductions in total cholesterol and LDL cholesterol. However, there was no significant effect on non-fatal myocardial infarction. The review found no significant effect of rehabilitation on smoking status or health-related quality of life (HRQoL). The quality of the trials was generally poor, with many studies having small sample sizes and unclear methods of randomization. The review concluded that exercise-based rehabilitation is effective in reducing cardiac deaths, but it is unclear whether exercise-only or comprehensive rehabilitation is more beneficial. The population studied was predominantly male, middle-aged, and low-risk, with limited data on ethnic diversity. The review highlights the need for larger, well-designed randomized controlled trials to confirm the effectiveness of rehabilitation in broader patient groups.Exercise-based rehabilitation for coronary heart disease (Review) by Jolliffe J, Rees K, Taylor RRS, Thompson DR, Oldridge N, Ebrahim S. This Cochrane review evaluates the effectiveness of exercise-based rehabilitation compared to usual care and comprehensive cardiac rehabilitation in reducing mortality, morbidity, and modifiable cardiac risk factors in patients with coronary heart disease. The review analyzed 8440 patients across 51 studies, with 36 trials of exercise-based rehabilitation and 16 trials of comprehensive rehabilitation. The results showed a 27% reduction in all-cause mortality for exercise-only rehabilitation and a 13% reduction for comprehensive rehabilitation. Total cardiac mortality was reduced by 31% and 26% respectively. Comprehensive rehabilitation also led to significant reductions in total cholesterol and LDL cholesterol. However, there was no significant effect on non-fatal myocardial infarction. The review found no significant effect of rehabilitation on smoking status or health-related quality of life (HRQoL). The quality of the trials was generally poor, with many studies having small sample sizes and unclear methods of randomization. The review concluded that exercise-based rehabilitation is effective in reducing cardiac deaths, but it is unclear whether exercise-only or comprehensive rehabilitation is more beneficial. The population studied was predominantly male, middle-aged, and low-risk, with limited data on ethnic diversity. The review highlights the need for larger, well-designed randomized controlled trials to confirm the effectiveness of rehabilitation in broader patient groups.