ExoCarta is a manually curated database of exosomal proteins, RNA, and lipids, providing information from both published and unpublished exosomal studies. It includes data on 11,261 protein entries, 2,375 mRNA entries, and 764 miRNA entries from 134 exosomal studies. The database also includes lipid entries, enhancing its utility for researchers. ExoCarta helps identify molecular signatures specific to certain tissue or cell type-derived exosomes and supports new exosomal studies. The database includes detailed information on exosomal isolation and purification procedures, aiding researchers in assessing the quality of exosomal preparations. ExoCarta is a free web-based resource that allows users to access information on exosomal molecular components, including gene ontology annotations, protein-protein interactions, and experimental descriptions. The database is updated regularly and includes data contributions from the exosomal scientific community. ExoCarta is expected to be updated with more exosomal studies and additional fields, such as protein-protein interactions and post-translational modifications. It will also function as an active news forum highlighting international scientific meetings and workshops related to exosomes. ExoCarta is freely available for download as tab-delimited files. Funding for the project comes from the National Health and Medical Research Council, Australia.ExoCarta is a manually curated database of exosomal proteins, RNA, and lipids, providing information from both published and unpublished exosomal studies. It includes data on 11,261 protein entries, 2,375 mRNA entries, and 764 miRNA entries from 134 exosomal studies. The database also includes lipid entries, enhancing its utility for researchers. ExoCarta helps identify molecular signatures specific to certain tissue or cell type-derived exosomes and supports new exosomal studies. The database includes detailed information on exosomal isolation and purification procedures, aiding researchers in assessing the quality of exosomal preparations. ExoCarta is a free web-based resource that allows users to access information on exosomal molecular components, including gene ontology annotations, protein-protein interactions, and experimental descriptions. The database is updated regularly and includes data contributions from the exosomal scientific community. ExoCarta is expected to be updated with more exosomal studies and additional fields, such as protein-protein interactions and post-translational modifications. It will also function as an active news forum highlighting international scientific meetings and workshops related to exosomes. ExoCarta is freely available for download as tab-delimited files. Funding for the project comes from the National Health and Medical Research Council, Australia.