Exosomes are small extracellular vesicles that carry proteins, lipids, and nucleic acids and can modulate recipient cell functions. They play a significant role in skin photoaging, which is caused by repeated UV exposure leading to skin damage. Exosomes are involved in aging-related processes such as oxidative stress, inflammation, and senescence. Stem cell-derived exosomes have shown therapeutic potential in skin photoaging by reducing MMP expression, increasing collagen and elastin production, and modulating signaling pathways. Exosomes can be used in cosmetics and therapies to rejuvenate skin. They have immunomodulatory effects, reduce oxidative stress, decrease senescence, and stimulate ECM components production. Exosomes are promising for treating skin photoaging due to their ability to transfer genetic material and modify cellular functions. They are also used as drug delivery vehicles and diagnostic biomarkers. Exosomes derived from various cells, including stem cells, have been shown to inhibit UV-induced damage, reduce MMP expression, and promote collagen synthesis. Exosomes have potential in skin repair and regeneration, and their clinical application is being explored. They can be delivered through topical applications, injections, or other methods. Exosomes are a promising therapeutic option for skin photoaging due to their ability to modulate cellular processes and reduce UV-induced damage.Exosomes are small extracellular vesicles that carry proteins, lipids, and nucleic acids and can modulate recipient cell functions. They play a significant role in skin photoaging, which is caused by repeated UV exposure leading to skin damage. Exosomes are involved in aging-related processes such as oxidative stress, inflammation, and senescence. Stem cell-derived exosomes have shown therapeutic potential in skin photoaging by reducing MMP expression, increasing collagen and elastin production, and modulating signaling pathways. Exosomes can be used in cosmetics and therapies to rejuvenate skin. They have immunomodulatory effects, reduce oxidative stress, decrease senescence, and stimulate ECM components production. Exosomes are promising for treating skin photoaging due to their ability to transfer genetic material and modify cellular functions. They are also used as drug delivery vehicles and diagnostic biomarkers. Exosomes derived from various cells, including stem cells, have been shown to inhibit UV-induced damage, reduce MMP expression, and promote collagen synthesis. Exosomes have potential in skin repair and regeneration, and their clinical application is being explored. They can be delivered through topical applications, injections, or other methods. Exosomes are a promising therapeutic option for skin photoaging due to their ability to modulate cellular processes and reduce UV-induced damage.