This study explores the integration of augmented reality (AR) in diagnostic imaging, examining its potential as a transformative tool in healthcare. The review highlights the growing role of AR in enhancing surgical precision, improving patient engagement, and customizing medical interventions. When combined with technologies like virtual reality (VR), artificial intelligence (AI), and robotics, AR opens new avenues for innovation in clinical practice, education, and training. However, the study also identifies numerous unanswered questions and areas requiring further research, including the clinical efficacy of AR-integrated interventions, optimization of surgical workflows, and technological challenges. The integration of AR into clinical settings is also influenced by regulatory and developmental factors, such as compliance with standards, safety regulations, risk management, clinical validation, and developmental processes. Addressing these aspects is crucial for a comprehensive understanding of the challenges and opportunities in AR integration. The study also notes the impact of the COVID-19 pandemic on the development of AR applications in healthcare, particularly in diagnostic imaging, where AR has facilitated remote learning, skill development, and improved patient care. The review of systematic studies reveals a growing interest in AR applications across various surgical domains, including orthopedics, neurosurgery, and oncology. Key findings include the potential of AR to enhance surgical precision, improve clinical outcomes, and support educational and training initiatives. However, challenges such as technical limitations, data security concerns, and ethical considerations remain to be addressed. The study emphasizes the need for continued research and development to fully realize the transformative potential of AR in medical imaging and healthcare delivery.This study explores the integration of augmented reality (AR) in diagnostic imaging, examining its potential as a transformative tool in healthcare. The review highlights the growing role of AR in enhancing surgical precision, improving patient engagement, and customizing medical interventions. When combined with technologies like virtual reality (VR), artificial intelligence (AI), and robotics, AR opens new avenues for innovation in clinical practice, education, and training. However, the study also identifies numerous unanswered questions and areas requiring further research, including the clinical efficacy of AR-integrated interventions, optimization of surgical workflows, and technological challenges. The integration of AR into clinical settings is also influenced by regulatory and developmental factors, such as compliance with standards, safety regulations, risk management, clinical validation, and developmental processes. Addressing these aspects is crucial for a comprehensive understanding of the challenges and opportunities in AR integration. The study also notes the impact of the COVID-19 pandemic on the development of AR applications in healthcare, particularly in diagnostic imaging, where AR has facilitated remote learning, skill development, and improved patient care. The review of systematic studies reveals a growing interest in AR applications across various surgical domains, including orthopedics, neurosurgery, and oncology. Key findings include the potential of AR to enhance surgical precision, improve clinical outcomes, and support educational and training initiatives. However, challenges such as technical limitations, data security concerns, and ethical considerations remain to be addressed. The study emphasizes the need for continued research and development to fully realize the transformative potential of AR in medical imaging and healthcare delivery.